Evidence map›Paper›PMID 40883618›Full record

SynthesisEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Arteriovenous fistula in the head and neck - a systematic review and meta-analysis of clinical presentation.

Jurriën L A Embrechts, Rilke J Snoeren, Joseph C J Bot, Birgit Lissenberg-Witte, Johannes C F Ket, C Rene Leemans, Remco de Bree

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jurriën L A EmbrechtsDepartment of Otolaryngology - Head and Neck Surgery, Amsterdam UMC, Location VUmc, Amsterdam, Netherlands. jla.embrechts@gmail.com.ORCID http://orcid.org/0000-0003-3032-6186
Rilke J SnoerenDepartment of Pulmonology, Hagaziekenhuis, The Hague, The Netherlands.
Joseph C J BotDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Location VUmc, Amsterdam, Netherlands.
Birgit Lissenberg-WitteAmsterdam UMC, Location VUmc, Epidemiology & Data Science, Amsterdam, Netherlands.
Johannes C F KetMedical Library, Vrije Universiteit, Amsterdam, Netherlands.
C Rene LeemansDepartment of Otolaryngology - Head and Neck Surgery, Amsterdam UMC, Location VUmc, Amsterdam, Netherlands.
Remco de BreeDepartment of Head and Neck Surgical Oncology, University Medical Center Utrecht, Utrecht, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify clinical characteristics, anatomical distribution and risk factors of arteriovenous fistula in the head and neck area (hAVF).

methodsA systematic review and meta-analysis on individual participant data of available literature from inception to September 2024 on extracranial and extradural hAVF was performed.

resultsThe systematic search resulted in an inclusion of 869 cases with a median age of 35 years and 58.5% being male. Overall 36.5% patients with a primary hAVF and 63.5% with a secondary hAVF were observed. The most common symptom at presentation is objective sound (thrill, bruit or murmur) in 59.8% patients. The vertebral artery (32.8%), superficial temporal artery (20.4%) and brachiocephalic or subclavian artery (10.1%) were the most common affected afferent vessels in the hAVFs. The internal (31.0%) and external (5.2%) jugular and brachiocephalic or subclavian vein (9.6%) are the most common affected efferent vessels. In the secondary group 43.1% developed the hAVF after invasive treatment of which 34.0% after insertion of a central venous catheter in the internal jugular vein, 8.4% after Implantable Cardioverter Defibrillator (ICD) or pacemaker lead removal, 4.2% after a hemodialysis catheter and 7.1% after hair transplantation surgery.

conclusionshAVFs are rare vascular malformations that can be differentiated into primary (congenital or spontaneous) and secondary (traumatic or iatrogenic) lesions. Patients often present with an objective sound (thrill, bruit or murmur) and symptoms that can be related to specific vessels. Secondary hAVF is almost twice as frequent compared to primary hAVF. There is a sex predilection of secondary hAVF towards males presenting more often with a traumatic hAVF. Iatrogenic risk factors such as intravenous catheter placement, hemodialysis catheter and pacemaker lead removal and hair transplantation surgery may contribute to the development of a secondary hAVF.

Indexed as

Arteriovenous FistulaHeadNeckHumansMaleRisk FactorsArteriovenous anomalyArteriovenous fistulaHead and neck

Identifiers

PMID40883618
PMCPMC12987781

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.