ArticleScientific reports2025
GC-MS profiling, in vitro and in silico antibacterial and antioxidant potential of crude secondary metabolites of an endophytic bacterium isolated from Enhydra fluctuans lour.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Harnessing the seaweed holobiont: antibacterial and antioxidant lead compounds from epiphytic microbiota.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Bacterial Metabolite-Derived NDM-1 Inhibitors: A Computational Strategy to Overcome β-Lactam Resistance.Probiotics and antimicrobial proteins · 2026Article
- A comprehensive review on bacterial endophytic secondary metabolites: a road map from crude extract to lead molecule production.Frontiers in pharmacology · 2026Review
- Antibacterial potential of epiphytic fungi obtained from brown algae of Kenyan coastal waters.PloS one · 2026Article
- Bioprospecting endophytic fungi,Science progressArticle
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Authors and funding
9 authors.
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Abstract
This study investigates the bioactive potential of secondary metabolites produced by endophytic bacteria isolated from Enhydra fluctuans Lour., a medicinal plant known for its antioxidant and antimicrobial properties. Fresh leaves were collected, surface-sterilized, and used to isolate bacterial endophytes. The isolates were identified morphologically and confirmed by 16S rRNA gene sequencing. Metabolites were extracted using ethyl acetate and assessed for antibacterial activity via the disc diffusion method and antioxidant capacity by DPPH radical scavenging assay. GC-MS was used to identify volatile bioactive substances. The isolate showed 91.75% similarity with Pseudomonas campi (NR_181172.1), indicating a distant relationship and suggesting it may represent a novel or uncharacterized taxon. The isolate was mostly sensitive to Ciprofloxacin (5 µg). Its ethyl acetate crude extract showed moderate antibacterial activity against Staphylococcus aureus with a 13.4 ± 0.21 mm inhibition zone at 500 µg/disc, compared to kanamycin (30 µg/disc). Antioxidant activity showed an IC
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