Evidence map›Paper›PMID 40883439›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2026

[18F]FDG PET/MR to assess disease extension and inflammation in children and young adults with primary ciliary dyskinesia.

Silvia Carraro, Valentina A Ferraro, Pietro Zucchetta, Stefania Zanconato, Francesca Serani, Chiara Giraudo, Diego Cecchin

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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Silvia CarraroUnit of Pediatric Respiratory Medicine and Allergy, Women's and Children's Health Department - SDB, University Hospital of Padua, Padova, Italy. silvia.carraro@unipd.it.ORCID 0000-0003-2284-1225
Valentina A FerraroUnit of Pediatric Respiratory Medicine and Allergy, Women's and Children's Health Department - SDB, University Hospital of Padua, Padova, Italy.ORCID 0000-0002-9840-8519
Pietro ZucchettaUnit of Nuclear Medicine, Department of Medicine -DIMED, University Hospital of Padua, Padova, Italy.
Stefania ZanconatoUnit of Pediatric Respiratory Medicine and Allergy, Women's and Children's Health Department - SDB, University Hospital of Padua, Padova, Italy.
Francesca SeraniUnit of Nuclear Medicine, Department of Medicine -DIMED, University Hospital of Padua, Padova, Italy.ORCID 0000-0001-7470-0614
Chiara GiraudoUnit of Advanced Clinical and Translational Imaging, Department of Cardiac, Thoracic, Vascular Sciences and Public Health - DCTV, University Hospital of Padua, Padova, Italy.ORCID 0000-0003-0924-5883
Diego CecchinUnit of Nuclear Medicine, Department of Medicine -DIMED, University Hospital of Padua, Padova, Italy.ORCID 0000-0001-7956-1924

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary ciliary dyskinesia (PCD) is a rare condition characterized by ciliary dysfunction, impaired mucociliary clearance and mucus accumulation in the airways. PURPOSE: Our aim was to evaluate the performance of [18F]FDG PET/MR in assessing structural and inflammatory pulmonary features in patients with PCD, using high-resolution CT (HRCT) as the gold-standard reference. MATERIALS AND

methodsWe recruited patients with PCD (≥ 7 years) regularly followed at our Regional Center for PCD. They underwent chest HRCT and [18F]FDG PET/MR using sequences optimized for the morpho-functional study of the lung. Parametric PET images were obtained by dividing each voxel by the mean value in a reference area. The volume of interest (VOI in cm

resultsSixteen patients were enrolled. The Bland-Altman plot showed good agreement between HRCT and MR scores. Cumulative HRCT and MR scores correlated significantly with SUV mean score (HRCT: p = 0.02, r

conclusionPET/MR proved to be accurate in evaluating disease extent in PCD. It enabled the simultaneous assessment of structural damage and lung inflammation, both of which resulted inversely related to lung function. PET/MR is a promising tool for PCD monitoring.

Indexed as

Fluorodeoxyglucose F18Magnetic Resonance ImagingMultimodal ImagingPositron-Emission TomographyAdolescentAdultChildFemaleHumansInflammationMaleYoung AdultFluorodeoxyglucose F18[18F]FDG PET/MRHRCTInflammation, childrenPrimary ciliary dyskinesia

Identifiers

PMID40883439
PMCPMC12860827

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.