Evidence map›Paper›PMID 40883366›Full record

ArticleScientific reports2025

GC-MS and HPLC chemical profile, antioxidant, anti-acetylcholinesterase, and anti-diabetic activities of Libyan Salvia lanigera herb extract and essential oil.

Fatma A Elshibani, Amr Farouk, Esra El Naili, Engy Mahmoud, Ahmed Othman, Hamdoon A Mohammed, Nagla Elkazza, Mohamed A Sharkasi, Nada A Alzunaidy

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fatma A ElshibaniDepartment of Pharmacognosy, Faculty of Pharmacy, University of Benghazi, Benghazi, Libya.
Amr FaroukFlavour and Aroma Chemistry Department, National Research Centre, Dokki, Giza, 12622, Egypt.
Esra El NailiDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Benghazi, Benghazi, Libya.ORCID http://orcid.org/0000-0002-2827-7621
Engy MahmoudFlavour and Aroma Chemistry Department, National Research Centre, Dokki, Giza, 12622, Egypt.
Ahmed OthmanDepartment of Pharmacognosy and Medicinal Plants, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
Hamdoon A MohammedDepartment of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Qassim University, Buraidah, 52571, Saudi Arabia. Ham.mohammed@qu.edu.sa.
Nagla ElkazzaDepartment of Pharmacology, Faculty of Pharmacy, Assalam International University, Benghazi, Libya.
Mohamed A SharkasiDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Benghazi, Benghazi, Libya.
Nada A AlzunaidyDepartment of Food Science and Human Nutrition, College of Agriculture and Food, Qassim University, Buraydah, 51452, Saudi Arabia. n.alznedy@qu.edu.sa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study explored the chemical composition and biological activities of the essential oil and ethanol extract of Salvia lanigera collected from Libya. The ethanol extract obtained from the wild growing S. lanigera was evaluated for the chemical composition via high-performance liquid chromatography with diode-array detection (HPLC-DAD), which demonstrated phenolic and flavonoid contents. A total of 17 compounds, representing phenolic and flavonoid derivatives, have been identified. Besides, gas chromatography-mass spectrometry (GC-MS) analysis of the essential oil obtained from S. lanigera aerial parts identified 24 compounds, accounting for 99.33% of the oil, and the major components were characterized to be 1,8-cineole (27.28%), camphor (25.82%), α-pinene (7.71%), and α-terpineol (7.67%). The results indicated that the oil and ethanol extract exhibited marked radical scavenging capacity toward DPPH (2,2-diphenyl-1-picrylhydrazyl), with IC

Indexed as

AntioxidantsCholinesterase InhibitorsHypoglycemic AgentsOils, VolatilePlant ExtractsSalviaAcetylcholinesteraseAnimalsChromatography, High Pressure LiquidFlavonoidsGas Chromatography-Mass SpectrometryGlycoside Hydrolase InhibitorsMolecular Docking SimulationAcetylcholinesteraseAntioxidantsCholinesterase InhibitorsFlavonoidsGlycoside Hydrolase InhibitorsHypoglycemic AgentsOils, VolatilePlant ExtractsAnti-cholinesterase activityAntidiabetic effectsAntioxidantsFlavonoidsHPLC-DADPhenolic acidsSalvia lanigera

Identifiers

PMID40883366
PMCPMC12397425

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.