Evidence map›Paper›PMID 40883274›Full record

ArticleNature communications2025

Dynamic pathways in energy landscapes guiding supramolecular Janus dendrimer self-assemblies between lamellar and cubic architectures.

Jiabin Luan, Danni Wang, Niels P Kok, Neshat Moslehi, Ilja K Voets, Daniela A Wilson

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiabin LuanInstitute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0001-6484-4083
Danni WangInstitute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0002-1612-7116
Niels P KokInstitute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands.
Neshat MoslehiLaboratory of Self-Organizing Soft Matter, Department of Chemical Engineering and Chemistry and Institute of Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, The Netherlands.
Ilja K VoetsLaboratory of Self-Organizing Soft Matter, Department of Chemical Engineering and Chemistry and Institute of Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, The Netherlands.ORCID http://orcid.org/0000-0003-3543-4821
Daniela A WilsonInstitute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands. d.wilson@science.ru.nl.ORCID http://orcid.org/0000-0002-8796-2274

Funding

EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) ERC-2020-CoG 101001965EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) ERC-CoG 101044434 "SynMoBio"Ministerie van Onderwijs, Cultuur en Wetenschap (Ministry of Education, Culture and Science, Netherlands) Gravitation program 024.001.035Ministerie van Onderwijs, Cultuur en Wetenschap (Ministry of Education, Culture and Science, Netherlands) Gravity program 024.005.020
6 · The paper itself

Abstract

Elaborate kinetic control enables supramolecular self-assemblies to deviate from equilibrium, depicting profound energy landscapes with remarkable structural and functional diversity. Despite this potential, achieving an energy landscape that encompasses lamellar and inverse cubic structures remains a significant challenge, contrasting with the sophisticated structural transformations naturally orchestrated by cellular systems. Here, we present a dynamic and minimalistic Janus dendrimer self-assembly system capable of reversibly transitioning between lamellar vesicles and inverse cubic structures. By exploiting temperature-triggered non-covalent interactions, including OEG interdigitation and hydrogen bonding, conformational flexibility, and molecular packing, we reveal a rich energy landscape featuring diverse assembly pathways spanning lamellar vesicles and inverse cubosomes. Our study not only enriches the structural versatility of Janus dendrimer assemblies but also provides a foundation for advancing supramolecular systems toward applications in biomedicine, catalysis, and beyond.

Identifiers

PMID40883274
PMCPMC12397278

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.