Evidence map›Paper›PMID 40882647›Full record

ArticleThe Lancet. Haematology2025

Estimated unit costs of anaemia interventions for women of reproductive age in 193 UN member states: a costing study.

Victoria L Oliver, Yingying Wang, Sumie Leung, Robin Blythe, Clare Glover-Wright, Jacinta Holloway-Brown, Michael Bode, Sant-Rayn Pasricha, Natalie Carvalho

Abstract read
In one paragraph

Article in The Lancet. Haematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Victoria L OliverMelbourne School of Population and Global Health, University of Melbourne, Parkville, VIC, Australia. Electronic address: tori.oliver@unimelb.edu.au.
Yingying WangMelbourne School of Population and Global Health, University of Melbourne, Parkville, VIC, Australia.
Sumie LeungWalter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Robin BlytheDuke-NUS Medical School, Singapore; School of Mathematical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.
Clare Glover-WrightMelbourne School of Population and Global Health, University of Melbourne, Parkville, VIC, Australia.
Jacinta Holloway-BrownSchool of Computer and Mathematical Sciences, University of Adelaide, Adelaide, SA, Australia.
Michael BodeSchool of Mathematical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.
Sant-Rayn PasrichaMelbourne School of Population and Global Health, University of Melbourne, Parkville, VIC, Australia; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Clinical Haematology, Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, Parkville, VIC, Australia.
Natalie CarvalhoMelbourne School of Population and Global Health, University of Melbourne, Parkville, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnaemia affects an estimated 1·92 billion people worldwide. The UN Sustainable Development Goals set targets for reducing anaemia prevalence by 50% in women of reproductive age, for whom the risks and consequences of anaemia are the greatest. Prioritisation of cost-effective anaemia reduction strategies relies on robust estimates of the costs of interventions. We aimed to develop country-specific unit cost estimates for WHO-recommended anaemia interventions for women of reproductive age.

methodsA micro-costing approach was used to estimate unit costs (per recipient per year) for six anaemia prevention and treatment interventions in 193 UN member states using data from secondary sources. The interventions included were oral iron supplementation for pregnant and non-pregnant women, fortification of staple foods, multiple micronutrient supplementation for pregnant women, intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine, presumptive deworming treatment for pregnant and non-pregnant women, and insecticide-treated bednets. A health-care sector perspective and 1-year timeframe were adopted. Cost categories included commodity, supply chain, service delivery, and administrative programme costs. Parameter uncertainty was explored in deterministic sensitivity analyses. Costs are presented as population-weighted means and SDs in 2023 US dollars.

findingsIn most countries, staple food fortification and deworming were the lowest cost interventions, with population-weighted average costs of less than US$1 per person per year in settings with the highest burden of anaemia (ranging from $0·27 [SD 0·25] for staple fortification in low-income-countries to $0·84 [0·21] for deworming in non-pregnant women in lower-middle-income countries). Multiple micronutrient supplements had the highest average unit costs in most countries, with unit costs ranging from $9·57 (SD 0·58) in low-income countries to $135·56 (SD 25·95) in high-income countries. Commodity and service delivery costs were the largest cost drivers, although this varied across interventions and settings.

interpretationOur standardised methodology and dataset estimate country-level unit costs and describe cost drivers for WHO-recommended anaemia interventions. These findings can facilitate cost-effectiveness analyses of anaemia interventions for women of reproductive age and strengthen priority-setting processes.

fundingGates Foundation.

Indexed as

AnemiaAdolescentAdultCost-Benefit AnalysisDietary SupplementsFemaleHealth Care CostsHumansMalariaPregnancyUnited Nations

Identifiers

PMID40882647
PMCPMC12405068

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.