Evidence map›Paper›PMID 40881899›Full record

ArticleWorld journal of clinical cases2025

Euglycemic diabetic ketoacidosis associated with etogliflozin in post-pancreatitis diabetes: A case report.

Jiang-Tao Chai, Xin-Hui Li, Zhao-Shun Jiang

Abstract readCase Reports
In one paragraph

Article in World journal of clinical cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jiang-Tao ChaiDepartment of Endocrinology, 960th Hospital of PLA, Jinan 250014, Shandong Province, China.
Xin-Hui LiDepartment of Endocrinology, 960th Hospital of PLA, Jinan 250014, Shandong Province, China.
Zhao-Shun JiangDepartment of Endocrinology, 960th Hospital of PLA, Jinan 250014, Shandong Province, China. jzs012@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSodium-glucose cotransporter-2 (SGLT-2) inhibitors improve cardiovascular and renal outcomes in diabetes but may induce euglycemic diabetic ketoacidosis (euDKA) CASE SUMMARY: A 29-year-old man with PPDM developed euDKA 1 week after initiating etogliflozin (5 mg/day). On admission, laboratory tests revealed blood ketones > 4.5 mmol/L, pH 7.1, and glucose 10.78 mmol/L. Discontinuation of SGLT-2 inhibitor, insulin pump therapy (basal 12 U/day, premeal bolus 4 U), aggressive hydration (6000 mL first 2 days), and nutritional support normalized ketosis and acidosis within 24 hours.

conclusionCaution is warranted with SGLT-2 inhibitors in PPDM. Insulin therapy is preferred to prevent euDKA.

Indexed as

Acute pancreatitisCase reportEtogliflozinEuglycemic diabetic ketoacidosisPost-pancreatitis diabetesSodium-glucose cotransporter-2

Identifiers

PMID40881899
PMCPMC12362423

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.