ArticleFrontiers in neurology2025
Interactive dynamic scalp acupuncture enhances brain functional connectivity in bilateral basal ganglia ischemic stroke patients: a randomized controlled trial.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The trial behind it
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Who cites it
3 citing papers in PubMed.
- Acupuncture for Post-Stroke Lower Limb Dysfunction: Clinical Efficacy and Neurophysiological Mechanisms.Journal of multidisciplinary healthcare · 2025Review
- Acupuncture for post-stroke recovery: a retrospective cohort study on motor function and quality of life.Frontiers in neurologyArticle
- Assessing efficacy and safety of dynamic scalp acupuncture for post-stroke rehabilitation: systematic review and meta-analysis protocol.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: This randomized controlled trial investigated the effects of interactive dynamic scalp acupuncture (IDSA) on brain functional connectivity density (FCD) in patients with bilateral basal ganglia ischemic stroke (BBGIS), focusing on its potential to enhance motor recovery. Methods: Seventy BBGIS patients (aged 45-75 years, 1-3 months post-stroke, Brunnstrom stage II-V) and 40 age-and sex-matched healthy controls (HCs) were enrolled. Resting-state functional MRI (rs-fMRI) assessed baseline FCD differences between groups, with regions showing significant alterations correlated to Fugl-Meyer Assessment (FMA) scores selected as seed points. Patients were randomized to IDSA ( Results: Compared to HCs, BBGIS patients exhibited reduced FCD in the right supplementary motor area (SMA_R) and right cerebellum-8 (C8_R), which positively correlated with FMA scores (r = 0.82 and r = 0.86, respectively; Conclusion: IDSA therapy enhances functional connectivity in SMA_R and C8_R, which are associated with motor recovery in BBGIS patients. These findings support IDSA as a potential intervention for stroke rehabilitation (Study registration: China National Clinical Trial Registry, ChiCTR2200055463).
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