ArticleFrontiers in neurology2025
Correlation between the hemoglobin-to-hematocrit ratio and 3-month outcomes in patients with acute ischemic stroke: a secondary analysis based on a prospective cohort study.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Our study dedicated to clarify the connection between the hemoglobin (HB) to hematocrit (HCT) (HB/HCT) ratio and adverse outcomes (AOs) in patients with acute ischemic stroke (AIS) within 3 months. Methods: A total of 1,906 individuals with AIS were encompassed at a hospital in South Korea. A binary logistic regression model (BLRM) was utilized to explore the linear relationship between the HB/HCT ratio and AOs in patients with AIS. Additionally, generalized additive models (GAMs) and smooth curve fitting were leveraged to investigate the nonlinear relationship between the HB/HCT ratio and AOs in patients with AIS. Two steps recursive method was adopted to calculate the inflection point. Results: There was a nonlinear relationship between the HB/HCT ratio (per 0.01) and AOs in AIS patients according to the GAMS score and smooth curve fitting. The inflection point of the HB/HCT ratio (per 0.01) is 33.191. On the left side of the inflection point, the risk of AOs decreased by 27.80% for every 1 unit increase in the HB/HCT ratio (per 0.01) (odds ratio (OR) = 0.722, 95% confidence interval (CI): 0.577, 0.903, Conclusion: Our study revealed a U-shaped relationship between the HB/HCT ratio and the prognosis of AIS. Monitoring HB/HCT ratio may be able to identify patients with AOs in advance, ultimately providing more reference of scientific and effective care for AIS patients which may be linked to the improvement of their clinical outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.