Evidence map›Paper›PMID 40881777›Full record

ArticleFrontiers in neurology2025

Pain experience and behavior management: efficacy of photobiomodulation as an adjunct to local anesthesia in MIH patients-a randomized split-mouth clinical study.

Aneta Olszewska, Magdalena Roszak, Aleksandra Szymczak, Elżbieta Paszyńska, Agata Czajka-Jakubowska

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Effectiveness of different anaesthetic techniques, agents and adjunctive interventions in handling pain during dental treatment of MIH-affected teeth: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aneta OlszewskaDepartment of Orthodontics and Temporomandibular Disorders, Poznan University of Medical Sciences, Poznań, Poland.
Magdalena RoszakDepartment of Computer Science and Statistics, Faculty of Medical Sciences, Poznan University of Medical Sciences, Poznań, Poland.
Aleksandra SzymczakDepartment of Integrated Dentistry and Community Dentistry, Poznań, Poland.
Elżbieta PaszyńskaDepartment of Integrated Dentistry and Community Dentistry, Poznań, Poland.
Agata Czajka-JakubowskaDepartment of Orthodontics and Temporomandibular Disorders, Poznan University of Medical Sciences, Poznań, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pain management in children with Molar-Incisor Hypomineralization (MIH) poses challenges for pediatric dentists. MIH affects the enamel of the first permanent molars and incisors, increasing the risk of cavities, hypersensitivity, and making anesthesia and dental treatments more difficult. Children with MIH often experience dental fear, necessitating effective pain management techniques. Photobiomodulation (PBM) has potential analgesic benefits in dentistry but requires further evaluation for its effectiveness in MIH cases. Aim: This study aimed to assess the impact of photobiomodulation on pain control in maxillary permanent molars affected by MIH. Methods: In our randomized split-mouth clinical study, 45 participants (25 males, 20 females) aged 7 to 15 years, with both maxillary molars affected by MIH, were assigned to either the intervention group (PBM plus standard anesthesia, Results: The PBM group reported significantly lower subjective pain (mean VAS 2 [1-5]) compared to the control group (6 [2-8]), Conclusion: Photobiomodulation improves pain management and the effectiveness of local anesthesia in maxillary molars affected by MIH by diminishing pain experience and enhancing anesthesia effects, providing a promising approach for pain control in children.

Indexed as

dental painlocal anesthesiamolar incisor hypomineralizationpain managementphotobiomodulation

Identifiers

PMID40881777
PMCPMC12380728

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.