Evidence map›Paper›PMID 40881750›Full record

ArticleWorld journal of transplantation2025

Extended travel for donor organs: Is cold static storage still relevant.

Montana Reynolds, Martin Gerard Walsh, Ervin Y Cui, Divyaam Satija, Doug A Gouchoe, Matthew C Henn, Kukbin Choi, Nahush A Mokadam, Asvin M Ganapathi, Bryan A Whitson

Abstract read
In one paragraph

Article in World journal of transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Montana ReynoldsCOPPER Laboratory, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43201, United States.
Martin Gerard WalshCOPPER Laboratory, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43201, United States.
Ervin Y CuiCOPPER Laboratory, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43201, United States.
Divyaam SatijaDivision of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43201, United States.
Doug A GouchoeCOPPER Laboratory, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43201, United States.
Matthew C HennDivision of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43201, United States.
Kukbin ChoiDivision of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43201, United States.
Nahush A MokadamDivision of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43201, United States.
Asvin M GanapathiDivision of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43201, United States.
Bryan A WhitsonDivision of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43201, United States. bryan.whitson@osumc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraditional limitations of cold static storage (CSS) on ice at 4 °C during lung transplantation have necessitated limiting cold ischemic time (CIT) to 4-6 hours.

aimTo determine the effect of CSS or EVLP on donors with extended travel distance [> 750 nautical miles (NM)] to recipient.

methodsLung transplants, whose donor traveled greater than 750 NM, were identified from the United Network for Organ Sharing Database. Recipients were stratified into either: CSS or EVLP, based on preservation method. Groups were assessed with comparative statistics and survival was assessed by Kaplan-Meier methods. A 3:1 propensity match was then created, and same analysis was repeated.

resultsPrior to matching, those in the EVLP group had significantly increased post-operative morbidity to include dialysis, ventilator use, acute rejection, and treated rejection in the first year (

conclusionWhile there was no significant difference in survival, EVLP patients had increased peri-operative morbidity. With the advent of changes in CSS with 10 °C storage further analysis is necessary to evaluate the best methods for utilizing organs from increased distances.

Indexed as

Cold static storageEx vivo lung perfusionIschemic timeMachine perfusionNormothermic perfusionTransplantation lungUnited Network for Organ Sharing

Identifiers

PMID40881750
PMCPMC12038590

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.