ReviewFrontiers in veterinary science2025
Alternatives to antibiotics for sustainable livestock production in the context of the One Health approach: tackling a common foe.
Review in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Effects of increasing doses of wood vinegar on feed intake, digestibility, ingestive behavior, nitrogen balance and serum biochemistry in sheep.Veterinary and animal science · 2026Review
- Mechanism of tea saponin regulating the Nrf2/HO-1/NQO1 pathway to alleviate Salmonella Enteritidis-induced intestinal pathological injury in chicks.Poultry science · 2026Article
- Antimicrobial peptides as sustainable alternatives to antibiotics in livestock production: implications for animal health in tropical and sub-tropical systems.Tropical animal health and production · 2026Review
- Toward a Theory of Proactive Health-Oriented Livestock Production: A Testable Conceptual Framework for Alpine Pastoral Systems.Life (Basel, Switzerland) · 2026Review
- Effects of a Phytogenic Water Supplement on Selected Cultivable Bacterial Populations and Intestinal Histomorphology in Ross 308 Broiler Chickens Challenged withLife (Basel, Switzerland) · 2026Article
- Effects of Dietary Wild Thyme Alone or Combined with Probiotic or Prebiotic Supplementation on Growth Performance, Immune Response, Oxidative Status, and Intestinal Health in Broiler Chickens.Veterinary sciences · 2026Article
- Applications and Action Mechanisms ofAnimals : an open access journal from MDPI · 2026Review
- Strategies for Reducing Antimicrobial Use in Cattle Through Gut Microbiome Modulation: A Systematic Review of Alternatives to Antibiotics.Animals : an open access journal from MDPI · 2026Review
- Dietary Capsiate-Producing Chili Pepper Promotes Somatic and Femoral Growth and Modulates Intestinal Immunometabolic Responses in Mice.Molecules (Basel, Switzerland) · 2026Article
- Article
- Phytosynbiotic Containing Double-Layer MicroencapsulatedAnimals : an open access journal from MDPI · 2026Article
- Growth performance, antioxidant capacity, and microbial modulation in broilers supplemented with Arabic gum under a small-scale production system.Open veterinary journal · 2026Article
- Effects of α-terpineol and 1,8-cineole fromFrontiers in veterinary science · 2026Article
- Mitigating antimicrobial resistance in the animal industry: reduction strategies and alternatives to antibiotics.Frontiers in veterinary science · 2026Review
- Syndrome-specific antimicrobial escalation and diagnostic stewardship gaps in large-scale Hungarian pig farms: a cross-sectional survey.Frontiers in veterinary science · 2026Article
- Microbiota-immune crosstalk in livestock: implications for tick-borne disease control.Frontiers in immunology · 2026Review
- From burden to action: Saudi Arabia's strategy on antimicrobial resistance.Open medicine (Warsaw, Poland) · 2026Review
- Effects on Rumen Microbial Population and Serum Biochemical Responses to Guanidinoacetic Acid,Animals : an open access journal from MDPI · 2025Article
- Sustainability of Animal Production Chains: Alternative Protein Sources as an Ecological Driver in Animal Feeding: A Review.Animals : an open access journal from MDPI · 2025Review
- Distribution of Aerosol Bacteria in Broiler Houses at Different Growth Stages During Winter.Animals : an open access journal from MDPI · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The discovery of the growth promoting effects of antibiotics in the 1940s contributed to the economic efficacy of the livestock industry. In response to increased animal protein demand from the 1950s, antimicrobial use at sub-therapeutic levels for growth promotion and disease prevention (antimicrobial growth promoter, AGP) improved feed-to-weight ratio, meat quality and overall health of livestock. These benefits encouraged the heavy use of AGPs such that about 70% of global use of antimicrobials was for food animals. Despite the numerous benefits of AGPs, the emergence of antimicrobial resistance (AMR) associated with their use and impact on human and livestock health, establishes AMR as a global health plague, affecting man, animal and the environment. Although many countries have banned the use of AGPs in livestock production, efforts to identify effective alternatives have yielded inconsistent findings and only few effective alternative products are currently available. This highlights the need to intensify efforts toward identifying more effective AGP alternatives. While current strategies focus on evaluating the efficacy of single products/class of products that can enhance productivity and health, future strategies should focus on combining multiple approaches. It is also important to acknowledge that no single alternative can fully replicate the same mechanism of action attributed to antimicrobials. This comprehensive review presents recent research findings on AGP use trend before and after bans in many countries, the benefit/mode of action of reported AGP alternatives, the economic impact of AGP alternatives in the context of the One Health approach, the factors militating the search for effective AGP alternatives, research gaps and future action plans for AGP-free animal farm management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.