Evidence map›Paper›PMID 40881590›Full record

ReviewFrontiers in cardiovascular medicine2025

Coronary microvascular dysfunction: a review of its association with extracardiac organ pathologies.

Yuting Duan, Jia Liu, Shan Wang, Tongxiao Luan, Jing Zhou, Ziwei Cui, Aohua Wang, Mengru Xu, Song Hu, Yongjun Mao

Abstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The Wound-Heart Axis: Can Chronic Wounds Contribute to Cardiac Dysfunction?International journal of molecular sciences · 2026
    Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuting DuanDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Jia LiuDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Shan WangDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Tongxiao LuanDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Jing ZhouDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Ziwei CuiDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Aohua WangDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Mengru XuDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Song HuQingdao University, Laoshan District, Qingdao, Shandong, China.
Yongjun MaoQingdao University, Laoshan District, Qingdao, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary microvascular dysfunction (CMD) is a high-risk factor for numerous cardiovascular events, and there is an increasing focus on the diagnosis and treatment of CMD itself or its association with cardiovascular diseases. However, some evidences suggest potential associations between CMD and multiple extracardiac pathologies, such as cerebrovascular, renal, pulmonary, retinal, hepatic, immune system diseases, and cancer. A shared pathological mechanism may underlie these connections, yet the relationship between CMD and other organs and systemic diseases remains unclear. Therefore, this review comprehensively assesses the current evidence base for the interplay between CMD and a range of systemic diseases, highlighting the need for a more integrated diagnostic and therapeutic approach.

Indexed as

cardiovascular diseasescoronary microvascular dysfunctionmicrovascular dysfunctionmyocardial ischemianon-obstructive coronary artery disease

Identifiers

PMID40881590
PMCPMC12380738

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.