Evidence map›Paper›PMID 40881589›Full record

ArticleFrontiers in cardiovascular medicine2025

Association between NoSAS score and cardiovascular disease in patients with obstructive sleep apnea.

Riken Chen, Jie Quan, Qiujing Tang, Zhaojun Chen, Zhongxing Hu, Yitian Yang, Wenxi Li, Yihuan Su, Huizhao Liao, Tingting Sun and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Riken Chen *Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Jie Quan *Neurology Department, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Qiujing Tang *Central Hospital of Guangdong Provincial Nongken, Zhanjiang, Guangdong, China.
Zhaojun Chen *Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Zhongxing HuThe First Clinical School of Medicine, Zhengzhou University, Zhengzhou, Henan, China.
Yitian YangDepartment of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Wenxi LiDepartment of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Yihuan SuDepartment of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Huizhao LiaoState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, China.
Tingting SunState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, China.
Qinghua ChenDepartment of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Yuli CaiDepartment of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Weilong YeDepartment of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Junfen ChengDepartment of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Wenliang ChenTranslational Medicine Center, Medical Interdisciplinary Science Research Center of Western Guangdong, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Weimin YaoDepartment of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Enlin YeDepartment of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Obstructive sleep apnea (OSA) is a common sleep-related respiratory disorder, yet many cases remain undiagnosed. Given the significant association between OSA and various adverse health outcomes, including cardiovascular complications, early identification and intervention are essential. The NoSAS score effectively screens individuals at high risk of OSA, thereby aiding in early detection. Material and methods: Data were collected from the Sleep Medicine Center at the First Affiliated Hospital of Guangzhou Medical University and the Sleep Research Institute at the Second Affiliated Hospital of Guangdong Medical University. Participants with a NoSAS score ≥8 were classified as high-risk, while those with scores <3 were classified as low-risk. Logistic regression was used to analyze the association between high-risk classification and cardiovascular disease morbidity. Result: A total of 2,164 participants with complete NoSAS score data were analyzed. In the high-risk group of 1,248 participants, cardiovascular disease incidence was 7.29%. In the adjusted model, the NoSAS high-risk group demonstrated a 2.2-fold increased risk of cardiovascular disease compared to the low-risk group (OR: 2.22, 95% CI: 1.17-4.18; Conclusion: In conclusion, the NoSAS high-risk group exhibited a higher burden of cardiovascular disease morbidity and served as an independent predictor of this condition.

Indexed as

cardiovascular diseasemorbidityNoSAS questionnaireobstructive sleep apnea (OSA)sleep-related respiratory disorder

Identifiers

PMID40881589
PMCPMC12380788

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.