Evidence map›Paper›PMID 40881583›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Gender differences in cognitive reserve: An impact on progression in subjective cognitive decline?

Giulia Giacomucci, Valentina Moschini, Alice Ceccarelli, Sonia Padiglioni, Carmen Morinelli, Salvatore Mazzeo, Chiara Crucitti, Giulia Galdo, Filippo Emiliani, Silvia Bagnoli and 5 more

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Giulia GiacomucciDepartment of Neuroscience Psychology, Drug Research and Child Health University of Florence Florence Italy.
Valentina MoschiniResearch and Innovation Centre for Dementia-CRIDEM AOU Careggi Florence Italy.
Alice CeccarelliUniversity of Florence Florence Italy.
Sonia PadiglioniResearch and Innovation Centre for Dementia-CRIDEM AOU Careggi Florence Italy.
Carmen MorinelliResearch and Innovation Centre for Dementia-CRIDEM AOU Careggi Florence Italy.
Salvatore MazzeoVita-Salute San Raffaele University Milan Italy.
Chiara CrucittiDepartment of Neuroscience Psychology, Drug Research and Child Health University of Florence Florence Italy.
Giulia GaldoDepartment of Neuroscience Psychology, Drug Research and Child Health University of Florence Florence Italy.
Filippo EmilianiDepartment of Neuroscience Psychology, Drug Research and Child Health University of Florence Florence Italy.
Silvia BagnoliDepartment of Neuroscience Psychology, Drug Research and Child Health University of Florence Florence Italy.
Assunta IngannatoDepartment of Neuroscience Psychology, Drug Research and Child Health University of Florence Florence Italy.
Elisa MarcantelliDepartment of Neuroscience Psychology, Drug Research and Child Health University of Florence Florence Italy.
Benedetta NacmiasDepartment of Neuroscience Psychology, Drug Research and Child Health University of Florence Florence Italy.
Sandro SorbiDepartment of Neuroscience Psychology, Drug Research and Child Health University of Florence Florence Italy.
Valentina BessiDepartment of Neuroscience Psychology, Drug Research and Child Health University of Florence Florence Italy.ORCID https://orcid.org/0000-0002-6176-3584

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study investigated gender differences in cognitive reserve (CR) in subjective cognitive decline (SCD) and examined the impact of gender-CR interaction on the risk of progression to mild cognitive impairment (MCI).

methodsWe enrolled 440 SCD patients and estimated CR using premorbid intelligence (

resultsWomen showed lower TIB scores than men ( DISCUSSION: Gender has an impact on CR, but not through socio-economic variables. In turn, CR influenced the risk of MCI progression, whereas gender did not. Highlights: Subjective cognitive decline (SCD) women presented lower cognitive reserve (CR) levels than men, despite similar education levels.Social-cultural factors did not explain these gender differences in CR in SCD.The gender-CR interaction was not mediated by social-cultural factors.The risk of progression to mild cognitive impairment (MCI) was influenced by CR but not by gender.

Indexed as

cognitive reservegendermild cognitive impairmentsubjective cognitive decline

Identifiers

PMID40881583
PMCPMC12381356

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.