ArticleCureus2025
Nonsurgical Retreatment of Endodontically Treated Teeth: A Prospective Cohort Study on Success Rates and Quality of Life.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Article
- Predicting outcomes of nonsurgical retreatment with artificial intelligence: A multicenter retrospective study using logistic regression, random forest, and extreme gradient boosting.Journal of conservative dentistry and endodontics · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe present study evaluated the clinical and patient-centered outcomes of nonsurgical retreatment of endodontically treated teeth. The primary goal was to assess the success rate, defined by clinical and radiographic criteria, while the secondary objectives focused on patient-reported quality-of-life outcomes using a validated oral health-related quality-of-life (OHRQoL) questionnaire. MATERIALS AND
methodsThis prospective cohort study was conducted from January 2024 to April 2025 at the Department of Conservative Dentistry and Endodontics and included 100 systemically healthy adults (aged 18-60 years) requiring retreatment of endodontically treated teeth. Patients with vertical root fractures, advanced periodontal disease, or non-restorable teeth were excluded. The procedure was performed using current/contemporary endodontic technologies such as rotary files, ultrasonic irrigation, and warm vertical compaction with gutta-percha and root canal sealer. Calcium hydroxide was used as an intracanal medication between visits. Outcomes were assessed six months after permanent restoration via clinical examinations and digital periapical radiographs, categorizing cases as healed, healing, or non-healing. OHRQoL scores were collected preoperatively and one- and six-months post-treatment using a modified questionnaire with a 1-5 Likert scale. Statistical analyses included Friedman's test for OHRQoL scores and Fisher's exact test for success rates with a significance level of p < 0.05.
resultsOf 100 patients, 88 (88%) patients achieved successful outcomes (healed, healing, or non-healing). Maxillary jaw retreatments outperformed mandibular jaw retreatments, and cases with periapical lesions had higher success rates than those without periapical lesions. No demographic or clinical factor significantly influenced the success rate (p > 0.05). Successful cases showed significant OHRQoL improvement (p = 0.001) from baseline (32.13 ± 12.07) to six months (19.40 ± 12.07), while failed cases showed no significant change (p = 0.425).
conclusionNonsurgical root canal retreatment in endodontically treated teeth achieved a high success rate with significant quality-of-life improvements in successful cases, underscoring the efficacy of standardized protocols and advanced technologies.
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