ArticleCureus2025
Pressure-Regulated Volume Control Ventilation Versus Pressure Control Ventilation on Oxygenation and Lung Dynamics of Neonates With Acute Respiratory Failure: A Quasi-experimental Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Impact of pressure -regulated volume control vs volume -controlled ventilation on respiratory mechanics in pediatric laparoscopic surgery: a randomized controlled trial.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction Acute respiratory failure in neonates presents as a critical challenge in neonatal intensive care units (NICUs), where mechanical ventilation plays a key role in management. Pressure control ventilation (PCV) is a conventional mode commonly used for ventilatory support. With technological advancements, newer modes such as pressure-regulated volume control (PRVC) have emerged, offering some potential benefits. However, studies comparing the effectiveness of PRVC to PCV in improving oxygenation and lung dynamics in neonates remain limited. This study aims to compare the effects of the PRVC mode to the PCV mode of ventilation in neonates with acute respiratory failure. Objective The objective of this study is to evaluate and compare the effectiveness of PRVC and PCV ventilation modes on oxygenation and lung dynamics in neonates with acute respiratory failure. We hypothesized that the PRVC mode would result in better oxygenation and lung dynamics compared to PCV in neonates with acute respiratory failure. Method This quasi-experimental study was conducted at the NICU of Bangladesh Shishu Hospital and Institute (BSH&I) from April 2023 to March 2025. A total of 60 neonates meeting the inclusion and exclusion criteria were enrolled and nonrandomly allocated into two groups: PRVC (n=30) and PCV (n=30). Oxygenation parameters (partial pressure of oxygen {PaO₂}, peripheral oxygen saturation {SpO₂}, fraction of inspired oxygen {FiO₂}, and PaO₂/FiO₂ {P/F} ratio), lung dynamics (compliance, driving pressure, and respiratory rate {RR}), arterial blood gas (ABG) values (pH, partial pressure of carbon dioxide {PaCO₂}, and bicarbonate {HCO₃}), and ventilator parameters (tidal volume (V
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