Evidence map›Paper›PMID 40881520›Full record

ReviewCureus2025

Allen Oldfather Whipple (1881-1963): A Pioneer of General Surgery.

Ledio Gjunkshi, Lorela Gjunkshi, Nadiya A Persaud, Sanjiv F Gray

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ledio GjunkshiResearch, Orlando College of Osteopathic Medicine, Winter Garden, USA.
Lorela GjunkshiResearch, Saba University School of Medicine, The Bottom, NLD.
Nadiya A PersaudResearch, Orlando College of Osteopathic Medicine, Winter Garden, USA.
Sanjiv F GraySurgery, Orlando College of Osteopathic Medicine, Winter Garden, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dr. Allen Oldfather Whipple (1881-1963) was a pioneer in general surgery whose innovative techniques transformed the management of pancreatic insulinomas and continue to shape modern surgical practices today. Born in Iran to missionary parents, Dr. Whipple later moved to the United States in pursuit of greater educational opportunities. He spent the majority of his medical career in New York, leaving a lasting impact on the world through his leadership and surgical expertise. Between the 1930s and 1940s, he developed the Whipple procedure (pancreaticoduodenectomy), which has since evolved through advances in surgical technique, instrumentation, and perioperative care to remain the gold standard for treating pancreatic head malignancies. In 1935, he also introduced the Whipple triad, which remains central in the diagnosis of insulinoma. Dr. Whipple served as president of several leading surgical organizations, including the American Surgical Association, where he advocated for surgical education reform and promoted standardization of operative techniques. He also authored three influential books: "Surgical Diagnosis," "Surgery of the Pancreas," and "Techniques of Abdominal Operations," which became foundational texts in surgical training. This historical vignette showcases the life and legacy of Dr. Allen Oldfather Whipple, highlighting his profound impact not only on his local hospital but also on the global medical community.

Indexed as

allen oldfather whipplepancreatic insulinomasurgical historywhipple procedurewhipple triad

Identifiers

PMID40881520
PMCPMC12382311

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.