ArticleCureus2025
Recurrence of Anti-melanoma Differentiation-Associated Gene 5 Antibody-Positive Dermatomyositis Following Long-Term Remission: A Report of Two Cases and Review of Literature.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report two cases of anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis (DM) that recurred after long-term remission. The first case involved a 41-year-old Japanese woman, and the other involved a 31-year-old Chinese woman. Both patients were initially treated with prednisolone, tacrolimus, and low-dose intravenous cyclophosphamide. Antibody negativity was confirmed during remission. However, DM recurred in both patients after 8 and 10 years, respectively, accompanied by the reappearance of anti-MDA5 antibodies. The Japanese patient exhibited severe liver dysfunction at both onset and recurrence. In contrast, the Chinese patient presented with clinically amyopathic DM and had mild respiratory and cutaneous symptoms at both time points. The recurrence patterns were similar in both cases. A review of recurrent anti-MDA5 antibody-positive DM cases revealed common features, including female predominance, mild interstitial lung disease, low serum ferritin levels, and relatively low cumulative cyclophosphamide doses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.