ArticleWorld journal of clinical cases2025
Splenic hamartoma mimicking angiosarcoma: A case report.
Article in World journal of clinical cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPrimary splenic lesions are rare and often detected incidentally through imaging, biopsy, or autopsy, typically without distinct clinical symptoms. Although imaging can help differentiate benign from malignant lesions, splenic hamartomas, and angiosarcomas may exhibit overlapping features, making diagnosis challenging. This report presents a case of splenic hamartoma suspected to be an angiosarcoma based on preoperative imaging. Splenic hamartomas that mimic angiosarcomas are exceedingly rare. CASE SUMMARY: A 33-year-old male presented to the Department of Emergency with frank red blood hematemesis and a 1-week history of epigastric pain. On arrival, he was alert and hemodynamically stable. Contrast-enhanced abdominal computed tomography revealed splenomegaly with significant engorgement of the portal and splenic veins, along with a diffuse nodular splenic lesion measuring 8.2 cm × 6.2 cm. Following esophageal varix ligation, abdominal magnetic resonance imaging demonstrated iso- to high-signal intensity within the splenic mass and multiple hypervascular lesions in the right hepatic lobe, raising suspicion for splenic angiosarcoma with hepatic metastases.
conclusionThis rare case of splenic hamartoma mimicking angiosarcoma highlights the importance of differential diagnosis in managing splenic tumors.
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