Evidence map›Paper›PMID 40881450›Full record

ArticleInternational journal of ophthalmology2025

One year clinical outcomes with a novel canaloplasty device in mild to severe open angle glaucoma.

Iden M Amiri, Heran W Gebreyesus, Nathan Grove, Jennifer L Patnaik, Malik Y Kahook, Leonard K Seibold

Abstract read
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Article in International journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Iden M AmiriDepartment of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado 80045, USA.
Heran W GebreyesusDepartment of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado 80045, USA.
Nathan GroveDepartment of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado 80045, USA.
Jennifer L PatnaikDepartment of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado 80045, USA.
Malik Y KahookDepartment of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado 80045, USA.
Leonard K SeiboldDepartment of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado 80045, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the one-year clinical outcomes of a novel canaloplasty device used in combination with cataract extraction (CE) in patients with mild to severe open angle glaucoma (OAG).

methodsThis study reviewed patients diagnosed with mild to severe OAG, who underwent canaloplasty with the STREAMLINE® Surgical System combined with CE. The primary outcome was surgical success, defined as achieving ≥20% intraocular pressure (IOP) reduction and/or a reduction of ≥1 glaucoma medication compared to baseline. Secondary outcomes included mean IOP, average number of glaucoma medications, and best-corrected distance visual acuity (BCDVA). Data was collected preoperatively and at multiple postoperative time points up to one year.

resultsA total of 68 eyes of 47 patients were included with mean age was 73.1±7.0y and 60% were females. Surgical success at one year was achieved in 68.8% of eyes, with 67.6% success in mild, 80.0% in moderate, and 66.7% in severe OAG cases. IOP was significantly reduced from a baseline of 16.1±0.5 to 14.7±0.4 mm Hg at one year (

conclusionCanaloplasty using the STREAMLINE® surgical system combined with CE effectively reduces IOP at one year in mild to severe OAG with minimal complications. IOP lowering efficacy, reduction in IOP lowering medications, and safety in moderate to severe OAG require further study.

Indexed as

canaloplastymicroinvasive glaucoma surgeryopen angle glaucomaSTREAMLINE Surgical System

Identifiers

PMID40881450
PMCPMC12378677

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