Evidence map›Paper›PMID 40881448›Full record

ArticleInternational journal of ophthalmology2025

Implantation of a posterior chamber phakic intraocular lens on Bruch's membrane opening-minimum rim width, retinal nerve fiber layer, and macular thickness.

Josefina Reñones, Humberto Carreras, Alfonso Antón-López, Ángel García-García, Rafael Melián, Juan Francisco Loro-Ferrer, David P Piñero

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Article in International journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Josefina ReñonesVithas Eurocanarias, Las Palmas de Gran Canaria 35005, Spain.
Humberto CarrerasVithas Eurocanarias, Las Palmas de Gran Canaria 35005, Spain.
Alfonso Antón-LópezInstitut Català de Retina, Barcelona 08022, Spain.
Ángel García-GarcíaVithas Eurocanarias, Las Palmas de Gran Canaria 35005, Spain.
Rafael MeliánVithas Eurocanarias, Las Palmas de Gran Canaria 35005, Spain.
Juan Francisco Loro-FerrerUniversidad de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria 35001, Spain.
David P PiñeroDepartment of Optics, Pharmacology and Anatomy, University of Alicante, 03690 San Vicente del Raspeig, Alicante, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess whether the implantation of a posterior chamber phakic intraocular lens produces changes in optical coherence tomography (OCT) measurements of macular thickness (MT) and two parameters that define the structure of the optic nerve, the peripapillary nerve fiber layer (RNFL) and the Bruch's membrane opening-minimum rim width (BMO-MRW).

methodsThis nonrandomized prospective pre-post study included 86 eyes of 48 patients (age, 20-47y; axial length: 23.10-28.95 mm) scheduled for myopia or myopic astigmatism correction with implantation of the implantable collamer lens (ICL). Eyes with glaucoma or any other ocular disease that could alter OCT results were excluded. RNFL, BMO-MRW and MT were measured preoperatively, and at 1 and 6mo after surgery using spectral-domain OCT. Changes between preoperative and postoperative values were evaluated.

resultsThere was a significant increase in BMO-MRW at 1mo (mean change: 3.48±15.07 µm,

conclusionMinimal changes are induced in BMO-MRW, RNFL and MT after ICL implantation in healthy eyes, confirming the safety of the surgical procedure regarding the structure of the optic nerve head and the macula, and indicating that this phakic intraocular lens seems to have a slight impact on OCT measurements.

Indexed as

implantable collamer lensmacular edemamacular thicknessoptical coherence tomographyphakic intraocular lensposterior chamber

Identifiers

PMID40881448
PMCPMC12378668

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.