Evidence map›Paper›PMID 40881445›Full record

ArticleInternational journal of ophthalmology2025

Clinical features and prognosis of carcinoma ex pleomorphic adenoma of the lacrimal gland: a comprehensive case series and literature review.

Run-Zi Yang, Ming-Shen Ma, Rui Liu, Ting-Ting Ren, Jing Li, Nan Wang, Liang-Yuan Xu, Qi-Han Guo, Jian-Min Ma

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Article in International journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Run-Zi YangBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Ming-Shen MaDepartment of Ophthalmology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
Rui LiuBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Ting-Ting RenBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Jing LiBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Nan WangBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Liang-Yuan XuBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Qi-Han GuoBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Jian-Min MaBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo examine carcinoma ex pleomorphic adenoma (CXPA) and its development to provide information for its clinical assessment and prognosis.

methodsThe clinical data of 26 patients with pathologically diagnosed CXPA were included for analysis. The patients' medical histories and data (

resultsThe average age of the 26 patients was 59.6±15.7y. There was no significant difference in the gender distribution. The incidence of CXPA bone destruction was approximately 57.7%, and the incidence of optic nerve involvement and extraocular muscle involvement was approximately 15.4% and 19.2%, respectively. The most common pathological type was adenocarcinoma (34.6%), followed by ductal carcinoma (26.9%). Five patients had recurrence or metastasis (19.2%). The 5-year recurrence-free survival rate was 59.0%. There were no significant differences in survival rates among patients with different pathologic types and stages (

conclusionCXPA has a variety of pathologic classifications, with characteristics of bone destruction and peripheral tissue invasion. Surgery combined with

Indexed as

125I radiation therapycarcinoma ex pleomorphic adenomalacrimal gland

Identifiers

PMID40881445
PMCPMC12378691

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