Evidence map›Paper›PMID 40881401›Full record

ArticleJACS Au2025

Bridged Azobenzene Exhibits Fully Reversible Photocontrolled Binding to a G‑Quadruplex DNA/Duplex Junction.

Javier Ramos-Soriano, Y Jennifer Jiang, Bowen Deng, Michael P O Hagan, Aditya G Rao, Doudou Lu, Susanta Haldar, A Sofia F Oliveira, Adrian J Mulholland, M Carmen Galan

Abstract read
In one paragraph

Article in JACS Au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Light-Controlled Folding and Chiroptical Sensing of G-Quadruplex DNA.The journal of physical chemistry letters · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Javier Ramos-SorianoSchool of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, United Kingdom.ORCID https://orcid.org/0000-0002-3054-0679
Y Jennifer JiangSchool of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, United Kingdom.
Bowen DengSchool of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, United Kingdom.
Michael P O HaganSchool of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, United Kingdom.
Aditya G RaoCentre for Computational Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, United Kingdom.
Doudou LuSchool of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, United Kingdom.
Susanta HaldarCentre for Computational Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, United Kingdom.
A Sofia F OliveiraCentre for Computational Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, United Kingdom.ORCID https://orcid.org/0000-0001-8753-4950
Adrian J MulhollandCentre for Computational Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, United Kingdom.ORCID https://orcid.org/0000-0003-1015-4567
M Carmen GalanSchool of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, United Kingdom.ORCID https://orcid.org/0000-0001-7307-2871

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability to selectively control DNA conformation using light as an external stimulus offers unique opportunities to control specific DNA sequences in biological settings and to develop nucleotide-based nanodevices. We describe a duplex/G-quadruplex (G4) junction-binding chemotype derived from a cyclic azobenzene core that reversibly photoswitches between

Indexed as

azobenzeneDNA nanodevicesG4/duplex DNA junctionphotoswitchsupramolecular DNA interactions

Identifiers

PMID40881401
PMCPMC12381718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.