Evidence map›Paper›PMID 40881345›Full record

ArticleFrontiers in cell and developmental biology2025

Keita Tanigaki, Tsukasa Tamamori, Naoko Sasaki, Risako Matsumura, Shunsuke Yamaga, Akito Sakanaka, Atsuo Amano, Michiya Matsusaki, Hiroki Takeuchi, Masae Kuboniwa

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Keita Tanigaki *Department of Preventive Dentistry, Graduate School of Dentistry, The Osaka University, Osaka, Japan.
Tsukasa TamamoriDepartment of Preventive Dentistry, Graduate School of Dentistry, The Osaka University, Osaka, Japan.
Naoko SasakiJoint Research Laboratory (TOPPAN) for Advanced Cell Regulatory Chemistry, Graduate School of Engineering, The Osaka University, Osaka, Japan.
Risako MatsumuraDepartment of Preventive Dentistry, Graduate School of Dentistry, The Osaka University, Osaka, Japan.
Shunsuke YamagaDepartment of Preventive Dentistry, The Osaka University Dental Hospital, Osaka, Japan.
Akito SakanakaDepartment of Preventive Dentistry, Graduate School of Dentistry, The Osaka University, Osaka, Japan.
Atsuo AmanoDepartment of Preventive Dentistry, Graduate School of Dentistry, The Osaka University, Osaka, Japan.
Michiya MatsusakiDepartment of Applied Chemistry, Graduate School of Engineering, The Osaka University, Osaka, Japan.
Hiroki Takeuchi *Department of Preventive Dentistry, The Osaka University Dental Hospital, Osaka, Japan.
Masae KuboniwaDepartment of Preventive Dentistry, Graduate School of Dentistry, The Osaka University, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Kostmann syndrome is an autosomal recessive disorder caused by a mutation of the Results: Examinations of immortalized human gingival epithelial (IHGE) cells showed HAX1 localization in mitochondria. In Conclusion: These results indicate that periodontal diseases complicated with Kostmann syndrome are induced by reduced JAM1 expression, caused by JAM1 being missorted into lysosomes by HAX1 dysfunction.

Indexed as

anticancer drugbarriercisplatinHAX1JAM1Kostmann syndromeperiodontitisPorphyromonas gingivalis

Identifiers

PMID40881345
PMCPMC12380812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.