Evidence map›Paper›PMID 40881244›Full record

ReviewWorld journal of clinical cases2025

Role of nitric oxide, prostaglandins, thromboxanes and endothelins in lung cancer: An overview.

Sadettin Demirel, Ipek Nazli Sinag

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of clinical cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Endogenous modulators in lung cancer.World journal of clinical cases · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sadettin DemirelMedicine School, Physiology Department, Bursa Uludag University, Bursa 16059, Türkiye. sdemirel@uludag.edu.tr.
Ipek Nazli SinagMedicine School, Physiology Department, Bursa Uludag University, Bursa 16059, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is the most frequent cause of cancer-related mortality worldwide. Nitric oxide (NO), prostaglandins (PGs), thromboxanes (TXs), and endothelins (ETs) participate in numerous physiological processes. These agents play an important role in lung carcinogenesis by regulating cancer cell proliferation, apoptosis, invasion, and angiogenesis. NO is a gaseous free radical with tumoricidal and tumorigenic activities in lung cancer. Arachidonic acid-derived PGs, including PGD

Indexed as

EndothelinsLung cancerNitric oxideProstaglandinsThromboxanes

Identifiers

PMID40881244
PMCPMC12243923

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.