Evidence map›Paper›PMID 40881241›Full record

ArticleWorld journal of clinical cases2025

Critical presentation of bradycardia, renal failure, atrioventricular nodal blockade, shock, and hyperkalemia syndrome: A case report.

Nicholas Thales Pavlatos, Pawan Daga, Zyad Smiley, Agastya Belur, Priyanka Bhattacharya, Rafay Khan

Abstract readCase Reports
In one paragraph

Article in World journal of clinical cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicholas Thales PavlatosDepartment of Internal Medicine, University of Louisville, Louisville, KY 40204, United States. ntpavl01@louisville.edu.
Pawan DagaDepartment of Internal Medicine, University of Louisville, Louisville, KY 40204, United States.
Zyad SmileyDepartment of Internal Medicine, University of Louisville, Louisville, KY 40204, United States.
Agastya BelurDepartment of Cardiovascular Medicine, University of Louisville, Louisville, KY 40204, United States.
Priyanka BhattacharyaDepartment of Cardiovascular Medicine, University of Louisville, Louisville, KY 40204, United States.
Rafay KhanDepartment of Cardiovascular Medicine, University of Louisville, Louisville, KY 40204, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBradycardia, renal failure, atrioventricular nodal blockade, shock, and hyperkalemia (BRASH) syndrome is an acronym used to describe a constellation of BRASH. It is an underrecognized phenomenon that can be deadly if not appropriately managed in a timely manner. This case highlights the importance of rapid diagnosis and reviews a multitude of treatment options in a uniquely severe case of BRASH syndrome. CASE SUMMARY: We present a case of a 54-year-old male on a beta-blocker and angiotensin-converting enzyme inhibitor who presented with one day history of nausea, vomiting, and shortness of breath. Upon presentation, he was bradycardic and hypotensive, requiring transcutaneous pacing. Initial electrocardiogram showed atrial fibrillation with ventricular rate in 30's. He was found to have acute kidney injury, hyperkalemia, and metabolic acidosis. He was successfully treated with multiple potassium lowering agents, continuous renal replacement therapy, four pressors, mechanical ventilation, and transvenous pacing with complete recovery prior to discharge.

conclusionIncreased awareness of BRASH syndrome may improve outcomes through timely diagnosis and aggressive intervention.

Indexed as

Acute kidney injuryAtrial fibrillationAtrioventricular nodal blockadeBradycardiaBradycardia, renal failure, atrioventricular nodal blockade, shock, and hyperkalemiaCardiogenic shockCase reportHyperkalemia-induced bradycardiaMultiorgan supportPolypharmacy

Identifiers

PMID40881241
PMCPMC12243919

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Registered trials

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