Evidence map›Paper›PMID 40881195›Full record

ArticleNature reviews. Materials2025

Materials and device strategies to enhance spatiotemporal resolution in bioelectronics.

Jing Zhang, Zhe Cheng, Pengju Li, Bozhi Tian

Abstract read
In one paragraph

Article in Nature reviews. Materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Designing PEDOT:PSS hydrogels for bioelectronic interfaces.Materials today (Kidlington, England) · 2026
    Article
  2. Article
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  5. Article
  6. Article
  7. Full-Stack Architectures for Intelligent Brain-Computer Interfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Soft electroceutical immunomodulation.National science review · 2026
    Article
  14. Review
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jing ZhangThe James Franck Institute, The University of Chicago, Chicago, IL, USA.ORCID 0009-0009-2575-5526
Zhe ChengDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.ORCID 0009-0000-2779-6895
Pengju LiPritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, USA.ORCID 0000-0002-0327-4758
Bozhi TianThe James Franck Institute, The University of Chicago, Chicago, IL, USA.ORCID 0000-0003-0593-0023

Funding

Multi-site photostimulation devices using porosity-based semiconductor heterojunctions for cardiac resynchronization therapyR01EB036091 · NIBIB · UNIVERSITY OF CHICAGO · PI Narutoshi Hibino, Bozhi Tian · 2024 to 2026
$1.8M
NIBIB NIH HHS R01 EB036091
6 · The paper itself

Abstract

Spatiotemporal resolution is a cornerstone of bioelectronics, enabling precise observation and control of biological events at the molecular, cellular and tissue levels. In this Review, we analyse recent advancements in spatiotemporal resolution essential for applications such as neuroprosthetics, cardiac monitoring and biosensing, with a focus on devices utilizing electrical, electrochemical and optoelectronic signal transduction. We define the intrinsic and extrinsic parameters of spatial and temporal resolution and highlight high-performance materials and device architectures - including electrodes, transistors and optoelectronic interfaces - that drive these capabilities. Strategies such as device miniaturization, 3D fabrication and multifunctional integration are evaluated for their capacity to improve resolution, particularly within the complex microenvironments of biological tissues. However, challenges persist, including signal interference, device stability and the demand for reliable long-term operation. Overcoming these obstacles requires continuous innovation in materials science, device engineering and computational approaches. Enhanced spatiotemporal resolution holds promise for advancing diagnostic precision, therapeutic responsiveness and our understanding of dynamic biological systems across biomedical disciplines.

Identifiers

PMID40881195
PMCPMC12382458

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.