Evidence map›Paper›PMID 40881178›Full record

ArticleJournal of biosciences and medicines2024

Oxidative Stress in Collegiate Cross Country Skiers in Mid- and Post-Seasons.

Scott P Jerome, Kriya L Dunlap, Ava M Parrish, Matthew L Lowman, Emily M Shipman, Lawrence K Duffy, Arleigh J Reynolds

Abstract read
In one paragraph

Article in Journal of biosciences and medicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Scott P JeromeDepartment of Chemistry & Biochemistry, University of Alaska Fairbanks, Fairbanks, AK, USA.
Kriya L DunlapDepartment of Chemistry & Biochemistry, University of Alaska Fairbanks, Fairbanks, AK, USA.
Ava M ParrishDepartment of Chemistry & Biochemistry, University of Alaska Fairbanks, Fairbanks, AK, USA.
Matthew L LowmanDepartment of Biology & Wildlife, University of Alaska Fairbanks, Fairbanks, AK, USA.
Emily M ShipmanDepartment of Biology & Wildlife, University of Alaska Fairbanks, Fairbanks, AK, USA.
Lawrence K DuffyDepartment of Chemistry & Biochemistry, University of Alaska Fairbanks, Fairbanks, AK, USA.
Arleigh J ReynoldsDepartment of Veterinary Medicine, University of Alaska Fairbanks, Fairbanks, AK, USA.

Funding

Biomedical Learning and Student Training (BLaST) ProgramUL1GM118991 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI HUEFFER, KARSTEN · 2015 to 2023
$19.0M
Biomedical Learning and Student Training (BLaST) ProgramRL5GM118990 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI HUEFFER, KARSTEN, REYNOLDS, ARLEIGH JAMES · 2015 to 2023
$10.5M
Biomedical Learning and Student Training (BLaST) ProgramTL4GM118992 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI HUEFFER, KARSTEN, REYNOLDS, ARLEIGH JAMES · 2015 to 2023
$7.1M
NIGMS NIH HHS RL5 GM118990NIGMS NIH HHS TL4 GM118992NIGMS NIH HHS UL1 GM118991
6 · The paper itself

Abstract

Purpose: The oxidative stress (OS) hypothesis of overtraining syndrome argues that increased production of free radicals through exercise cause muscle fatigue and damage resulting in lower athletic performance. Several studies have investigated OS immediately before and after exercise bouts in a training macrocycle. Our study aimed to compare OS of endurance athletes between a competition macrocycle and the immediate post-season recovery macrocycle. In addition, we aimed to identify athletes who experienced an unexplainable drop in athletic performance during the competition season in order to compare their OS to those who experienced no drop in performance. Methods: Fifteen members of the University of Alaska Fairbanks cross country ski team volunteered for this study. Blood samples were taken in early February ("mid-season") and late April ("post-season"). Participants completed questionnaires regarding physical activity and athletic performance at the time of the blood draws. Plasma was analyzed for 4-hydroxynonenal (HNE), nitrotyrosine, nitric oxide (NOX), and superoxide dismutase (SOD). Significance was determined by Wilcoxon and Mann-Whitney tests. Results: Participants displayed significantly higher (p < 0.05) SOD activity in the post-season (0.02065 U/mL ± 0.006477 SEM) as compared to mid-season (0.04459 U/mL ± 0.005860). Six athletes reported an unexplainable drop in performance (6D). In the post-season, HNE concentration was significantly higher (p < 0.05) for 6D (197.5 μg/mL ± 22.79) than for participants who did not report such a drop (69.80 μg/mL ± 33.59). 6D SOD activity was significantly higher in post-season (0.05048 U/mL ± 0.004688) than mid-season (0.01241 U/mL ± 0.006469). Conclusion: Signs of oxidative stress and mitigation during the post-season recovery macrocycle were higher in athletes who reported experiencing a drop in athletic performance during the competition season macrocycle.

Indexed as

4-HydroxynonenalAthletic PerformanceOxidative StressSuperoxide DismutaseTraining Macrocycle

Identifiers

PMID40881178
PMCPMC12381902

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.