ArticleFrontiers in genetics2025
Genetic analysis of non-syndromic peg lateralis using whole-exome sequencing.
Article in Frontiers in genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Genome-wide association study of molecular markers related to keel length in a specialized strain of yellow feathered broilers.Poultry science · 2026Article
- MSX1 and PAX9 Polymorphisms and Their Association With Lateral Incisor Morphology in Patients With Maxillary Canine Impaction.Medical science monitor : international medical journal of experimental and clinical research · 2026Observational
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7 authors.
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Abstract
Introduction: Although peg-shaped lateral incisors are a common dental anomaly, the genetic mechanisms governing peg lateralis are poorly understood, particularly in cases where other associated anomalies are absent. Here, we aimed to identify potential candidate genes contributing to the development of non-syndromic peg lateralis via whole-exome sequencing (WES). Methods: Saliva samples were collected from 20 unrelated Korean individuals with non-syndromic peg lateralis. WES was conducted on these samples, and variants with Results: We identified a heterozygous allele for Conclusion: The results suggest a possible function of these newly identified genes in the development of peg lateralis, which remains to be defined. This study may provide new insights into the genetic basis of non-syndromic peg lateralis, establishing a basis for the further analysis of the disease-associated genes identified herein.
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