Evidence map›Paper›PMID 40881118›Full record

ArticleSmart materials in medicine2024

Externally triggered drug delivery systems.

Huiyang Hu, Prabhakar Busa, Yue Zhao, Chao Zhao

Abstract read
In one paragraph

Article in Smart materials in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
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  9. Article
  10. Spatiotemporal cancer controlNanomedicine (London, England) · 2026
    Review
  11. Article
  12. Review
  13. Review
  14. Nanomedicines Against Mitochondrial Dysfunction-Induced Metabolic Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Huiyang HuDepartment of Chemical and Biological Engineering, University of Alabama, Tuscaloosa, AL, 35487, USA.
Prabhakar BusaDepartment of Chemical and Biological Engineering, University of Alabama, Tuscaloosa, AL, 35487, USA.
Yue ZhaoSchool of Computer Science, College of Science, Mathematics and Technology, Wenzhou-Kean University, Wenzhou, China.
Chao ZhaoDepartment of Chemical and Biological Engineering, University of Alabama, Tuscaloosa, AL, 35487, USA.

Funding

Equipment Supplement - Cold triggered Local Anesthesia for Pain ManagementR01GM144388 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Chao Zhao · 2022 to 2026
$1.8M
NIGMS NIH HHS R01 GM144388
6 · The paper itself

Abstract

Externally triggered drug delivery systems empower patients or healthcare providers to utilize external stimuli to initiate drug release from implanted systems. This approach holds significant potential for clinical disease management, offering appealing features like enhanced patient adherence through the elimination of needles and medication reminders. Additionally, it facilitates personalized medicine by granting patients control over the timing, dosage, and duration of drug release. Moreover, it enables precise drug delivery to targeted locations where external stimuli are applied. Advances in materials science, nanotechnology, chemistry, and biology have been pivotal in driving the development of these systems. This review presents an overview of the progress in research on drug release systems responsive to external stimuli, such as light, ultrasound, magnetic fields, and temperature. It discusses the construction strategies of externally triggered drug delivery systems, the mechanisms governing triggered drug release, and their applications in disease management.

Indexed as

External stimuli-responsiveHydrogelNanoparticlesOn-demand drug deliveryTemperature-sensitive polymers

Identifiers

PMID40881118
PMCPMC12382459

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.