ArticleWorld journal of clinical pediatrics2025
Aerobic fitness, lipid ratio, visceral adiposity index and risk of hypertension in adolescents: An observational study.
Article in World journal of clinical pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundHypertension (HTN) is a significant global health concern due to its rising prevalence and associated risks of cardiovascular disease, chronic kidney disease, and other comorbidities. The increasing rates of HTN among youth have been partly attributed to the global rise in childhood obesity, lipid abnormalities, and sedentary lifestyles.
aimTo investigate the independent associations of aerobic fitness (AF), the triglyceride-to-high-density lipoprotein cholesterol (TG/HDL-C) ratio, visceral adiposity index (VAI), and resting blood pressure (BP) in Nigerian adolescents.
methodsA multistage sampling technique was used to select 403 in-school adolescents aged 11-19 years in Kogi East, Nigeria. Participants were assessed for AF, TG/HDL-C ratio, VAI, systolic BP (SBP), and diastolic BP (DBP). The associations between the independent variables and the risk of systolic and diastolic HTN were examined using multivariate regression models, controlling for age and maturity status. Receiver operating characteristics curve (ROC) and area under the curve (AUC) were employed to determine the predictive capacities of the independent variables.
resultsThe overall prevalence of systolic HTN was 5.5% (girls: 7%; boys: 4%) while diastolic HTN was 12.7% (girls: 16.9%; boys: 8.4%). Among girls, all independent variables showed significant associations with SBP, including fitness (
conclusionAF, dyslipidemia, and visceral adipose tissue dysfunction were independently associated with the risk of HTN in Nigerian adolescents. These findings highlight the importance of promoting a healthy diet and encouraging aerobic physical activity among adolescents to reduce the risk of HTN.
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