Evidence map›Paper›PMID 40880946›Full record

ReviewPrecision chemistry2023

Atomically Precise Water-Soluble Gold Nanoclusters: Synthesis and Biomedical Application.

Qian Yan, Zhaotong Yuan, Yating Wu, Chunmei Zhou, Yihu Dai, Xiaoyue Wan, Dan Yang, Xu Liu, Nianhua Xue, Yan Zhu and 1 more

Abstract readReview
In one paragraph

Review in Precision chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Applications of AuNanomaterials (Basel, Switzerland) · 2024
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qian YanInstitute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, China.
Zhaotong YuanInstitute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, China.
Yating WuInstitute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, China.
Chunmei ZhouInstitute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, China.
Yihu DaiInstitute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, China.ORCID https://orcid.org/0000-0002-1223-5144
Xiaoyue WanInstitute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, China.ORCID https://orcid.org/0000-0001-7033-5525
Dan YangInstitute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, China.
Xu LiuSchool of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.ORCID https://orcid.org/0000-0003-0668-5074
Nianhua XueSchool of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
Yan ZhuSchool of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.ORCID https://orcid.org/0000-0002-5993-4110
Yanhui YangInstitute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, China.ORCID https://orcid.org/0000-0001-6470-6983

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atomically precise water-soluble gold nanoclusters (Au NCs) protected by organic ligands have attracted growing attention in serving as unique nanomaterials with the potential to generate theranostic tools (bioimaging, biosensing, and biotherapy), due to their ultrasmall size, superior photoluminescence, good biocompatibility, and nontoxicity. More importantly, Au NCs afford a well-defined atomic packing structure and molecular purity, providing a superior platform to unravel the structure-performance correlations for biodistribution, biological pharmacokinetics, and excretion of Au NCs. In this Review, we mainly survey the synthesis of water-soluble Au NCs and the recent progress in biomedicine of Au NCs, including bioimaging, biosensing, and biotherapy. The effects of ligand and size on the biomedical properties are discussed in detail. We hope that the advances in this research area can expand the applications of Au NCs in biomedicine.

Indexed as

biodiagnosticGold nanoclustertheranosticwater-solublewell-defined structure

Identifiers

PMID40880946
PMCPMC12382416

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.