ArticleNature reviews bioengineering2025
Multifunctional bioelectronics for brain-body circuits.
Article in Nature reviews bioengineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Design, Construction, and Application of Implantable Fiber Biosensors.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Silicon-Embedded Multifunctional Heterogeneous Integration for Miniaturized Photoplethysmography Detection Devices.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Engineering brain organoids: from neurodevelopmental modeling to translational barriers.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2026Review
- Targeted Magnetic Nanodiscs for Wireless Causal Manipulation of Gut-Brain Circuits.bioRxiv : the preprint server for biology · 2026Article
- From Physical Replacement to Biological Symbiosis: Evolutionary Paradigms and Future Prospects of Auditory Reconstruction Brain-Computer Interfaces.Micromachines · 2026Review
- In vivo multimodal neurochemical interfaces for real-time decoding of brain circuit.Nature reviews. Neuroscience · 2026Review
- Advancing neuroengineering with Neuromorphic Twins.Nature communications · 2026Review
- Emerging Implantable Sensor Technologies at the Intersection of Engineering and Brain Science.Biosensors · 2025Review
- Review
- Article
- Reliability and stability of Bioelectronic Medicine: a critical and pedagogical perspective.Bioelectronic medicine · 2025Review
- Central and peripheral neural circuits regulating glucose homeostasis.npj biomedical innovations · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The brain continuously receives, integrates, and responds to an influx of sensory signals emerging from the internal organs. This is mediated not only through direct neuronal connections defined by the peripheral nervous system, but also endocrine, humoral, metabolic, and immune pathways. Despite being predominantly imperceptible, the complex brain-body cross-talk is essential to maintaining physiological homeostasis. Moreover, it is increasingly recognized to play a critical role in cognitive and behavioral functions as well as in disorders of the nervous system. The functional and anatomical diversity of brain-body pathways necessitates the development of multifunctional implantable neurotechnologies that can facilitate causal studies during behavior. Although ubiquitous in studies of brain function, electrical, optical, and chemical interrogation of organ-brain circuits remains a challenge. In this review, we discuss recent developments in multifunctional implantable neurotechnologies, highlighting material selection, device architectures, integration challenges, and power and data transfer approaches necessary to establish robust bioelectronic interfaces to brain and peripheral organs suitable for long-term studies of brain-body signaling.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.