Evidence map›Paper›PMID 40880816›Full record

SynthesisFrontiers in psychology2025

Limited and inconclusive effects of computer-based neurocognitive training on PTSD, comorbid depression and executive functioning: a systematic review and meta-analysis.

Patric Muschner, Lena Goldschmidt, Luisa Sophie Gröning, Gerd-Dieter Willmund, Martina Piefke

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Patric Muschner *Neurobiology and Genetics of Behavior, Department of Psychology and Psychotherapy, Witten/Herdecke University, Witten, Germany.
Lena Goldschmidt *Neurobiology and Genetics of Behavior, Department of Psychology and Psychotherapy, Witten/Herdecke University, Witten, Germany.
Luisa Sophie GröningNeurobiology and Genetics of Behavior, Department of Psychology and Psychotherapy, Witten/Herdecke University, Witten, Germany.
Gerd-Dieter WillmundDepartment of Psychiatry, Psychotherapy, German Armed Forces Hospital, Berlin, Germany.
Martina PiefkeNeurobiology and Genetics of Behavior, Department of Psychology and Psychotherapy, Witten/Herdecke University, Witten, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with posttraumatic stress disorder (PTSD) and comorbid depression often experience neurocognitive deficits. While computer-based neurocognitive training (c-bnt) has shown benefits in primary depression, its efficacy for PTSD remains unclear. This meta-analysis evaluated the impact of c-bnt on PTSD severity, comorbid depression, and neurocognitive functions. A systematic review following PRISMA guidelines was conducted across databases (PsycINFO, PubMed, Scopus, PubPsych) from February to June 2025, focusing on randomized controlled trials (RCTs) involving PTSD and c-bnt. Bias risk was assessed using the revised Cochrane Risk-of-Bias Tool, and effect sizes were calculated with Cohen's

Indexed as

adjuvant therapyaffective disorderdepressionexecutive function trainingmeta-analysisposttraumatic stress disordersystematic reviewtrauma treatment

Identifiers

PMID40880816
PMCPMC12381773

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.