ArticleFrontiers in nutrition2025
Association between the Dietary Index for Gut Microbiota and periodontitis: mediation by systemic inflammation.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- From health to periodontitis: dynamic changes in the subgingival microbiome and their association with systemic inflammation levels.Frontiers in cellular and infection microbiology · 2026Article
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Authors and funding
7 authors.
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Abstract
Objective: This study aimed to explore the association between the Dietary Index for Gut Microbiota (DI-GM) and periodontitis, and to investigate the mediating role of systemic inflammation in this relationship. Methods: We performed a cross-sectional analysis using data from the National Health and Nutrition Examination Survey (NHANES) 2009-2014, including 9,022 participants. DI-GM scores were derived from 14 dietary components known to influence gut microbiota. Periodontitis was defined using a reduced version of the Centers for Disease Control and Prevention and American Academy of Periodontology criteria. Multivariable logistic regression and restricted cubic spline (RCS) analyses were employed to assess the association between DI-GM and periodontitis. Additionally, mediation analysis was performed to examine the contribution of systemic inflammation biomarkers to the observed associations. Results: Higher DI-GM scores were inversely associated with periodontitis prevalence, with each 1-point increase in DI-GM reducing the odds of periodontitis by 5% (95% CI: 0.92-0.97; Conclusion: Our findings indicate that greater adherence to DI-GM is associated with lower periodontitis prevalence, partly mediated by systemic inflammation, highlighting dietary modulation of gut microbiota as a potential strategy for periodontal disease prevention.
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