ArticleMaedica2025
Corneal Topography - a Review of Available Investigation Methods and Impact in the Diagnosis and Follow-Up of Keratoconus.
Article in Maedica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- V-Cornea: A computational model of corneal epithelium homeostasis, injury, and recovery.PLoS computational biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Keratoconus is a bilateral non-inflammatory ectatic disease of the cornea, with an asymmetrical evolution, that occurs in young people during puberty, progressing during the second and third decades and stabilizing around the age of 40. It is characterised by an insidious and progressive thinning of the cornea, myopia and astigmatism, which lead to a decrease in visual acuity. Slit-lamp examination findings in the early stages of keratoconus may appear normal. However, in advanced stages of untreated keratoconus, visual acuity is diminished, which leads to a lower quality of life. Corneal topography is essential in the early diagnosis of the disease, analyzing the corneal geometry and thus helping to establish the method of treatment and to follow patients' evolution. This investigation combines the projection of a light source and a video capture system of corneal images with computer processing, providing maps of the distribution of dioptric power over the entire surface of the cornea. Topography can be classified into measuring the anterior surface of the cornea (keratometry and reflection-based topography) as well as both the anterior and posterior surfaces of the cornea (Scheimpflug slit-lamp scanning and pinhole optics). Understanding and reading corneal topographies is essential in correctly diagnosing and staging a keratoconus case. The present review constitutes a comprehensive evaluation of available methods and expected typical results and interpretation, in order to support clinicians in better managing this underdiagnosed ectasia affecting young patients.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.