Evidence map›Paper›PMID 40880710›Full record

ArticleMaedica2025

Exploring the Knowledge and Attitudes of Physicians on Polypharmacy and Deprescribing in Clinical Practice: a Cross-Sectional Study.

Madhavi Eerike, Gerard Marshall Raj, Priyadharsini Rajendran, Veena Nayak, Paul Mathai, Vijaya Kumar Karra, Sakthivadivel Varatharajan, Rekha Priyadarshini, Gomathi Ramaswamy, Venugopalan Gunasekaran and 11 more

Abstract read
In one paragraph

Article in Maedica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Madhavi EerikeDepartment of Pharmacology, All India Institute of Medical Sciences (AIIMS), Bibinagar, Hyderabad, Telangana, India.
Gerard Marshall RajDepartment of Pharmacology, All India Institute of Medical Sciences (AIIMS), Bibinagar, Hyderabad, Telangana, India.
Priyadharsini RajendranDepartment of Pharmacology, JIPMER, Puducherry, India.
Veena NayakDepartment of Pharmacology, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Paul MathaiDepartment of Pharmacology, Malabar Medical College, Calicut, Kerala, India.
Vijaya Kumar KarraDepartment of Pharmacology, All India Institute of Medical Sciences (AIIMS), Bibinagar, Hyderabad, Telangana, India.
Sakthivadivel VaratharajanGeneral Medicine, All India Institute of Medical Sciences (AIIMS), Bibinagar, Hyderabad, Telangana, India.
Rekha PriyadarshiniDepartment of Pharmacology, All India Institute of Medical Sciences (AIIMS), Bibinagar, Hyderabad, Telangana, India.
Gomathi RamaswamyDepartment of Community Medicine and Family Medicine, All India Institute of Medical Sciences (AIIMS), Bibinagar, Hyderabad, Telangana, India.
Venugopalan GunasekaranGeriatric Medicine, JIPMER, Puducherry, India.
Jayachandran SelvarajDepartment of Medicine, JIPMER, Puducherry, India.
Sandhiya SelvarajanClinical Pharmacology, JIPMER, Puducherry, India.
Anu ChandranDepartment of Pharmacology, Malabar Medical College, Calicut, Kerala, India.
Shivanand KattimaniDepartment of Psychiatry, JIPMER, Puducherry, India.
Rijesh PotangadiDepartment of Orthopedics, Malabar Medical College, Calicut, Kerala, India.
Surendran Padinchara KunhipilakkandiyGeneral Medicine, Malabar Medical College, Calicut, Kerala, India.
Narayanan Puthiya VeettilDepartment of Pharmacology, Malabar Medical College, Calicut, Kerala, India.
Raghavendr RaoGeneral Medicine, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Mukhyaprana PrabhuGeneral Medicine, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Jerin Jose CherianClinical Studies and Trials Unit, Division of Development Research, Indian Council of Medical Research, Ansari Nagar, New Delhi, India.
Tanu AnandClinical Studies and Trials Unit, Division of Development Research, Indian Council of Medical Research, Ansari Nagar, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Polypharmacy, defined as the use of five or more medications, is increasingly prevalent among geriatric patients due to the complexity of managing multiple chronic conditions. This study aimed to evaluate physicians' knowledge of deprescribing, their familiarity with deprescribing tools and the factors influencing the deprescribing process. Materials and methods: This cross-sectional survey was conducted among 290 physicians from four prominent tertiary care centers in South India between October 2023 and March 2024. A self-administered semi-structured questionnaire was employed to evaluate physicians' knowledge of polypharmacy, attitudes toward fall-risk-increasing drugs (FRIDs) and practices related to deprescribing interventions. Data collection was managed using Microsoft Excel, while descriptive and bivariate analyses were performed using SPSS to analyze the findings. Results: The study revealed that a majority of physicians (148; 51.0%) were unfamiliar with the term "deprescribing" and reported no formal training in the practice. Analysis based on physicians' knowledge scores showed that participants with higher scores (≥28) demonstrated significantly greater awareness of the Tool to Improve Medications in the Elderly via Review (TIMER) and Fit fOR The Aged (FORTA) list compared to those with lower scores. Among these more knowledgeable physicians, 48.1% (n=13; p=0.054) were aware of TIMER but had not utilized it in practice, while 33.3% (n=9; p=0.016) reported familiarity with the FORTA list without its practical application. Conclusion: Deprescribing plays a vital role in managing polypharmacy and minimizing its associated risks in the aging population. However, its adoption is constrained by significant barriers, including a lack of awareness, insufficient formal training and limited integration of evidence-based deprescribing tools into clinical practice.

Identifiers

PMID40880710
PMCPMC12347019

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.