ArticleCase reports in gastroenterology
A Case of Turmeric-Induced Hepatotoxicity with Hyperferritinemia.
Article in Case reports in gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Rarely reported cases of hepatotoxicity associated with turmeric- and curcuminoid-containing dietary supplements: a comprehensive review by USP.Pharmaceutical biology · 2026Review
- Evaluation of subacute toxicity of highly bioavailable curcuRouge® formulation by a repeated dose 28-day oral exposure toxicology study in sprague dawley rats with safety assessment.Toxicology reports · 2026Article
- Probiotics and Phytoantioxidants as Emerging Neuroprotective Strategies: Bridging the Therapeutic Gap in Open Heart Surgery-Induced Brain Injury.Biomedicines · 2026Review
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Authors and funding
5 authors.
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Abstract
Introduction: We present the first published case of turmeric-associated drug-induced liver injury (DILI) accompanied by significant ferritin elevation. Case Presentation: Our patient, a 59-year-old female with DILI caused by long-term ingestion of oral turmeric supplements, presented with painless jaundice on an annual exam. The patient's liver function tests exhibited a hepatocellular pattern and hyperferritinemia (>2,000 ng/dL). Additional testing was negative except for heterozygosity for the H63D allele associated with hemochromatosis. A liver biopsy indicated acute hepatitis without fibrosis or stainable iron. Conclusion: Upon discontinuation of the supplement, liver enzymes normalized within a month. This case highlights the potential for hepatotoxicity and hyperferritinemia from curcumin toxicity, particularly when combined with additives like black pepper that enhance its bioavailability. Awareness of this phenomenon, particularly in heterozygous carriers of hemochromatosis, is crucial for diagnosis and optimal management.
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