Evidence map›Paper›PMID 40880628›Full record

ArticleFrontiers in cellular and infection microbiology2025

Endometrial microbiome during early pregnancy among women with and without chronic endometritis: a pilot study.

Hong Gao, Na Lu, Yahui Chen, Genlin Li, Huanhuan Li, Innie Chen, Amanda Black, Jenna Gale, Daniel J Corsi, Xiaolan Wang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Microbe on the move:Journal of bacteriology · 2026
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hong GaoScientific Research Department, The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Na LuSchool of Nursing, University of South China, Hengyang, Hunan, China.
Yahui ChenSchool of Nursing, University of South China, Hengyang, Hunan, China.
Genlin LiCenter for a combination of Obstetrics and Gynecology & Reproductive Medicine, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Huanhuan LiDepartment of Gynecology, The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Innie ChenOttawa Hospital Research Institute, the Ottawa Hospital, Ottawa, ON, Canada.
Amanda BlackDepartment of Obstetrics and Gynecology, University of Ottawa, Ottawa, ON, Canada.
Jenna GaleOttawa Hospital Research Institute, the Ottawa Hospital, Ottawa, ON, Canada.
Daniel J CorsiOttawa Hospital Research Institute, the Ottawa Hospital, Ottawa, ON, Canada.
Xiaolan WangCenter for a combination of Obstetrics and Gynecology & Reproductive Medicine, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Kristin ConnorDepartment of Health Sciences, Carleton University, Ottawa, ON, Canada.
Shi Wu WenOttawa Hospital Research Institute, the Ottawa Hospital, Ottawa, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Although chronic endometritis (CE) is strongly associated with infertility and adverse pregnancy outcomes, the specific microbiome of women with CE who can conceive remain unclear. Methods: This study recruited 100 participants aged 18 to 45 years with spontaneously conceived pregnancy who opted for pregnancy termination, detected their endometrial microbiome by 16S rRNA, and made a diagnosis of CE. Results: Among them, 19 were diagnosed with CE. There was a comparable microbial composition within the endometrium between women with and without CE. The relative abundance of Discussion: In women with CE, reproductive potential may be associated with the compositional stability of the endometrial microbiome, whereas an imbalance in the abundance of these microbes may be linked to their pregnancy outcomes.

Indexed as

BacteriaEndometritisEndometriumMicrobiotaAdolescentAdultChronic DiseaseFemaleHumansMiddle AgedPilot ProjectsPregnancyRNA, Ribosomal, 16SYoung AdultRNA, Ribosomal, 16S16S rRNAchronic endometritisearly pregnancyendometrial microbiomehost factors

Identifiers

PMID40880628
PMCPMC12380780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.