ReviewWorld journal of critical care medicine2025
Early enteral nutrition in critically-ill patients.
Review in World journal of critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Agmatine induces mitophagy via the PTS-I2R pathway to increase autophagic flux and attenuate sepsis-induced intestinal epithelial cell apoptosis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Article
- Sarcopenia and Frailty in COPD: Mechanisms, Relationship with Malnutrition and Potential Therapeutic Interventions.Nutrients · 2026Review
- The "cytokine storm" in infection and sepsis: win the battle but lose the war.Military Medical Research · 2026Review
- Development and evaluation of a machine learning-based risk prediction model for enteral feeding intolerance in sepsis patients.Frontiers in nutrition · 2026Article
- Efficacy of multimodal rehabilitation strategies on gastrointestinal function recovery in postoperative aortic dissection patients: a narrative review.Frontiers in physiology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Critically ill patients have a variety of complex pathologies and are in a multifarious state of catabolism supplanted by external and internal factors. Early enteral nutrition (EEN) is defined as the initiation of enteral feeding within 24-48 hours of hospitalization. Previous studies show the benefits of EEN include supporting the healing process through preservation of the gut mucosa, modulation of the immune response, and suppression of inflammation. However, recent studies suggest the advantages of EEN may not be as robust as previously believed. This review aims to discuss the outcomes of EEN when used in different critical care settings while managing complex disease states such as burns, sepsis, pancreatitis, and upper gastrointestinal bleeding. Evidence indicates that EEN has a positive impact on patient outcomes, hospital costs, length of intensive care unit stay, and preventing complications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.