Observational studyPloS one2025
Changes in patient-reported outcomes (PROs) and fecal calprotectin levels in patients with inflammatory bowel disease following a three-week gastrointestinal inpatient rehabilitation.
Observational study in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Uncovering Hidden Patterns of Stigma Amongst Older Men With Urinary Incontinence: A Latent Profile Analysis.International journal of nursing practice · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInflammatory bowel diseases (IBD) pose a considerable burden on patients and society. Rehabilitation programs are increasingly being considered as a complementary treatment. However, empirical evidence on the effectiveness of this approach is still sparse. We therefore investigated changes in patient-reported outcomes and an objective biomarker throughout a three-week inpatient gastrointestinal rehabilitation.
methodsWe conducted a longitudinal prospective observational study with a pretest-posttest design. Patients completed questionnaires on their subjective health-related quality of life (HRQoL), psychological distress, disease-specific burden, and work ability. Stool samples were collected to determine fecal calprotectin levels. Mean level changes were analyzed by means of t tests for repeated measurements, while differential changes between Crohn's disease and ulcerative colitis patients were compared using analysis of variance.
resultsSubjective disease burden and psychological distress decreased over the course of rehabilitation, whereas HRQoL and work ability increased. Fecal calprotectin levels slightly rose and were not meaningfully related to changes in subjective perception of illness.
conclusionsWe present evidence on rehabilitation as an important treatment in people with IBD in terms of subjective disease burden and various indicators of personal well-being. Furthermore, we advise against the use of fecal calprotectin as a marker for monitoring disease activity in short-term rehabilitation settings.
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Registered trials
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