Evidence map›Paper›PMID 40880350›Full record

ArticlePloS one2025

Effectiveness of radiofrequency and exercise-based rehabilitation on symptoms associated with pelvic floor dysfunction in breast cancer patients: A study protocol.

Cristina Salar-Andreu, Sergio Montero-Navarro, Ana Lozano-Rubio, Sonia Del Rio-Medina, Jose M Botella-Rico, María Torres-Lacomba, Josep C Benítez-Martínez, Jesús Sánchez-Más, Cristina Orts-Ruiz

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06694519 (Effectiveness of Radiofrequency and Exercise-based Rehabilitation on Symptoms Associated With Pelvic Floor Dysfunction in Breast Cancer Patients.), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06694519 narecruitingnot on this map

Effectiveness of Radiofrequency and Exercise-based Rehabilitation on Symptoms Associated With Pelvic Floor Dysfunction in Breast Cancer Patients.

TypeinterventionalSponsorSERGIO MONTERO NAVARRORan2025 to 2027Enrolled117ConditionsBreast Cancer, Genitourinary Syndrome, Radiofrequency, Physical ExerciseArmsmanometry through the PHENIX series device (model: PHENIX LIBERTY, manufacturer: ELECTRONIC CONCEPT LIGNON INNOVATION, Montpelier, France)., PFIQ-20 questionnaire (Pelvic Floor Impact Questionnaire Short Form), ICIQ-SF (International Consultation on Incontinence Questionnaire - Short Form), Sandvik's test
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cristina Salar-AndreuPhysical Therapy Department, Health Sciences Faculty, CEU-Cardenal Herrera University, CEU Universities, Elche, Valencia, Spain.
Sergio Montero-NavarroPhysical Therapy Department, Health Sciences Faculty, CEU-Cardenal Herrera University, CEU Universities, Elche, Valencia, Spain.
Ana Lozano-RubioPhysical Therapy Department, Health Sciences Faculty, CEU-Cardenal Herrera University, CEU Universities, Elche, Valencia, Spain.
Sonia Del Rio-MedinaPhysical Therapy Department, Health Sciences Faculty, CEU-Cardenal Herrera University, CEU Universities, Elche, Valencia, Spain.
Jose M Botella-RicoPhysical Therapy Department, Health Sciences Faculty, CEU-Cardenal Herrera University, CEU Universities, Elche, Valencia, Spain.
María Torres-LacombaFaculty of Medicine and Health Sciences, Physiotherapy and Nursing Department, University of Alcalá, Madrid, Spain.
Josep C Benítez-MartínezResearch Group on Physiotherapy Technology and Recovering (FTR), University of Valencia, Valencia, Spain.ORCID https://orcid.org/0000-0002-5118-0668
Jesús Sánchez-MásBiomedical Sciences Department, Health Sciences Faculty, CEU-Cardenal Herrera University, CEU Universities, Elche, Valencia, Spain.ORCID https://orcid.org/0000-0002-7739-2976
Cristina Orts-RuizPhysical Therapy Department, Health Sciences Faculty, CEU-Cardenal Herrera University, CEU Universities, Elche, Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast cancer is currently the most diagnosed type of cancer in the world, with a five-year survival rate of 90%. Survivors develop genitourinary dysfunction symptoms due to cancer treatment, which implies that they have to endure physical and psychological sequelae, with a negative impact on their quality of life. We present a study protocol to verify the effect of radiofrequency (RF) and pelvic floor muscle training (PFMT) for the treatment of genitourinary dysfunction in breast cancer survivors. METHODS/

designThis is a double-blind, three-arm, randomised clinical trial (Registration: NCT06694519). Participants from two breast cancer associations from Alicante (Spain) will be randomly assigned to one of the three intervention groups (RF, PFMT, RF + PFMT). It will include survivors aged ≥ 18 years who present pelvic dysfunction assessed by the Pelvic Floor Distress Inventory questionnaire (PFDI20) ≥ 100. Pelvic muscle strength, pelvic function, vaginal symptoms, sexual function, self-esteem and quality of life will be evaluated before the intervention, with follow-up at 15 days, 6 months and 1 year after the intervention. EXPECTED

resultsRF could offer additional benefits to PFMT due to its proven effectiveness in the treatment of vaginal dryness and dyspareunia. The expected results will have a positive impact on the health and well-being of women with breast cancer, reducing the symptomatology associated with the disease and its treatment, and improving their quality of life, as well as providing value for the development of more effective treatment protocols.

trial registrationClinicalTrials.gov NCT06694519.

Indexed as

Breast NeoplasmsExercise TherapyPelvic FloorPelvic Floor DisordersAdultAgedCancer SurvivorsDouble-Blind MethodFemaleHumansMiddle AgedQuality of LifeRandomized Controlled Trials as Topic

Identifiers

PMID40880350
PMCPMC12396660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.