ReviewPhysiological reviews2026
The evolving pathophysiology of bronchopulmonary dysplasia.
Review in Physiological reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Inhaled budesonide and beclomethasone for the prevention and treatment of bronchopulmonary dysplasia in very preterm infants: a prospective randomized controlled trial.Frontiers in pediatrics · 2026Trial
- Epigenetic programming in bronchopulmonary dysplasia: a framework linking early-life exposures to persistent lung disease-a narrative review.Pediatric research · 2026Review
- Lung Ultrasound in Bronchopulmonary Dysplasia: Diagnostic Tool, Prognostic Marker or Monitoring Strategy?Children (Basel, Switzerland) · 2026Review
- [Efficacy of fluconazole prophylaxis for late-onset invasive fungal infection in very preterm infants/very low birth weight infants: a retrospective cohort study based on propensity score matching].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026Article
- The Diagnostic Value of Lung Ultrasound in Bronchopulmonary Dysplasia Among Preterm Infants with Gestational Age ≤ 28 Weeks.Diagnostics (Basel, Switzerland) · 2026Article
- Mapping the evolving landscape: a bibliometric analysis of macrophages research in bronchopulmonary dysplasia (1990-2025)-a Web of Science Core Collection-based study.Translational pediatrics · 2026Article
- Mesenchyme-derived inflammation during the saccular stage recruits macrophages and alters lung development.JCI insight · 2026Article
- A Candidate Salivary miRNA Panel for Bronchopulmonary Dysplasia in Very and Extremely Low-Birth-Weight Preterm Infants: A Pilot Exploratory Study.Life (Basel, Switzerland) · 2026Article
- TLR9-mediated innate immune signaling contributes to acetaminophen-induced injury in the developing lung.American journal of physiology. Lung cellular and molecular physiology · 2026Article
- Gut dysbiosis modulates hyperoxia-induced bronchopulmonary dysplasia by promoting EMT through activating TLR4/NF-κB pathway.Molecular medicine (Cambridge, Mass.) · 2026Article
- Predicting bronchopulmonary dysplasia is complicated (as it should be): toward a framework for integrating physiological data.Pediatric research · 2026Article
- Association between multi-oil fat emulsion and bronchopulmonary dysplasia in preterm infants <32 weeks.Translational pediatrics · 2026Article
- Phototherapy, Morbidity, and Mortality in Very Preterm Newborns.JAMA network open · 2026Article
- Comment on "Umbilical Artery Leucine-Rich α-2 Glycoprotein as a Predictor of Bronchopulmonary Dysplasia in Preterm Infants".Pediatric pulmonology · 2026Article
- SLC25A28 Ameliorates Hyperoxic Lung Injury by Improving Mitochondrial Oxidative Phosphorylation in Alveolar Epithelial Cells.International journal of molecular sciences · 2026Article
- Lung Function Trajectories After Preterm Birth: A Life-Course Approach to Age-Specific Monitoring.Children (Basel, Switzerland) · 2026Review
- Flavin adenine dinucleotide increases antioxidant availability and protects neonatal C57Bl6 lungs from high oxygen induced lung injury.American journal of physiology. Cell physiology · 2026Article
- A nomogram to predict bronchopulmonary dysplasia in very preterm and/or very low birth weight infants with early-onset sepsis.BMC pediatrics · 2026Observational
- Pulse Oximetry Histogram Profiles Before and After Red Blood Cell Transfusion in Very Preterm Infants: A Prospective Observational Cohort.Children (Basel, Switzerland) · 2026Article
- The molecular mechanisms of gas signaling molecules in bronchopulmonary dysplasia related lung injury.Frontiers in cell and developmental biology · 2026Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Bronchopulmonary dysplasia (BPD) is the most common morbidity in very preterm infants and is characterized by abnormal development of the lung. The pathophysiology of BPD is primarily due to the effects of placental dysfunction, hyperoxia, ventilator-induced lung injury, poor nutrition, abnormal blood flow, and genomic/epigenomic factors on an immature lung. These adverse factors act on multiple cell types through many interacting signaling pathways. Abnormal development impacts most structures of the lung, including the alveoli, blood vessels, and airways, and frequently results in long-term impairment of lung mechanics and function. In this review, we provide a detailed overview of the processes involved in lung development and function and how these pathways are disrupted in BPD. The resulting effects on lung histology and lung mechanics and gas exchange are described. Insights derived from recent molecular and cellular characterization of lungs derived from normal and BPD-affected infants indicate possible mechanisms of pathogenesis and suggest potential new therapeutic strategies. The long-term implications of abnormal lung development as seen in BPD on later childhood and adult life are discussed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.