Evidence map›Paper›PMID 40880074›Full record

ArticleChembiochem : a European journal of chemical biology2025

Novel Platinum(II) Tetrazine Complex Capable of Live-Cell IEDDA Reaction.

Paul D O'Dowd, Dan Wu, Alby Benny, Ellen King, Alice Harford, Brendan Twamley, Olga Piskareva, Donal F O'Shea, Darren M Griffith

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Novel Platinum(II) Tetrazine Complex Capable of Live-Cell IEDDA Reaction.Chembiochem : a European journal of chemical biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paul D O'DowdDepartment of Chemistry, Royal College of Surgeons in Ireland, Dublin 2, D02 YN77, Ireland.ORCID https://orcid.org/0000-0003-3269-4388
Dan WuDepartment of Chemistry, Royal College of Surgeons in Ireland, Dublin 2, D02 YN77, Ireland.
Alby BennyDepartment of Chemistry, Royal College of Surgeons in Ireland, Dublin 2, D02 YN77, Ireland.ORCID https://orcid.org/0000-0002-4087-2394
Ellen KingCancer Bioengineering Group & Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, Dublin, D02 YN77, Ireland.
Alice HarfordSchool of Chemical and BioPharmaceutical Sciences, TU Dublin, Grangegorman, Dublin, D07 H6K8, Ireland.
Brendan TwamleyDepartment of Chemistry, Trinity College Dublin, Dublin 2, D02 PN40, Ireland.
Olga PiskarevaCancer Bioengineering Group & Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, Dublin, D02 YN77, Ireland.ORCID https://orcid.org/0000-0003-4466-0441
Donal F O'SheaDepartment of Chemistry, Royal College of Surgeons in Ireland, Dublin 2, D02 YN77, Ireland.ORCID https://orcid.org/0000-0003-0594-4193
Darren M GriffithDepartment of Chemistry, Royal College of Surgeons in Ireland, Dublin 2, D02 YN77, Ireland.ORCID https://orcid.org/0000-0002-5546-7244

Funding

Science Foundation Ireland under Grant numbers 12/RC/2275_P2Science Foundation Ireland under Grant numbers 21/FFP-P/10216
6 · The paper itself

Abstract

The development of the first Pt(II) tetrazine complex, trans-[Pt(II)Cl

Indexed as

Antineoplastic AgentsOrganoplatinum CompoundsPlatinumCell Line, TumorCell SurvivalCycloaddition ReactionFluorescent DyesHumansMicroscopy, FluorescenceMolecular StructureOptical ImagingAntineoplastic AgentsFluorescent DyesOrganoplatinum CompoundsPlatinumFLIMfluorescenceIEDDAplatinumtetrazine

Identifiers

PMID40880074
PMCPMC12447375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.