ArticleSpine deformity2026
Patient-specific biomechanical modeling of intraoperative scoliosis correction on the 2-year outcomes for thoracolumbar/lumbar vertebral body tethering.
Article in Spine deformity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Lumbar vertebral body tethering: 2-year multicenter radiographic and reoperation outcomes.Spine deformity · 2026Article
- Scoliosis Induction in the Porcine Spine Using a Growth-Modulating Posterior Tether: Finite Element Model Development and Calibration.Annals of biomedical engineering · 2026Article
- Evaluation of Curve Flexibility Using Scoliotic Spines Generated From a Generic Spine Model.International journal for numerical methods in biomedical engineering · 2026Article
- Toward biomechanically optimized intraoperative correction in lumbar vertebral body tethering.Spine deformity · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
purposeTo biomechanically assess the influence of intraoperative correction and presenting Sanders maturity scores (SS) on growth modulation correction after 2 years in pediatric idiopathic scoliosis treated with Vertebral Body Tethering (VBT).
methodsLumbar VBT was simulated using patient-specific finite element models (FEMs) from 20 cases of pediatric idiopathic scoliosis (average thoracolumbar/lumbar Cobb 47°; min: 34°, max: 63°), calibrated for preoperative SS, weight, and spine flexibility. The validated FEM included lateral decubitus positioning and VBT instrumentation at the actual upper instrumented vertebra (UIV: T9-T12) and lower instrumented vertebra (LIV: L2-L4). Simulations tested three intraoperative nominal correction levels (35, 50, and 70%) across SS stages (3A, 3B, 4, 5), with immediate and 2-year postoperative corrections computed and analyzed.
resultsA 35% intraoperative correction resulted in an immediate post-operative Cobb angle of 37° (23°-54°) but led to under-correction, with a final deformity of 38° (22°-63°) at 2 years. Curve progression occurred in 40% of SS3A cases, particularly in heavier patients (54 kg vs. 38 kg, p < 0.05). A 50% intraoperative correction yielded an immediate post-operative Cobb angle of 27° (16°-40°), with significant improvement at 2 years only in SS3A (p < 0.05). Clinically successful growth modulation (>5° improvement) correlated with lower weight (40 ± 6 kg vs. 54 ± 6 kg, p < 0.05). A 70% intraoperative correction produced an immediate post-operative Cobb angle of 17° (11°-22°) and significant improvement across all SS levels (p < 0.05), with final 2-year angles of 1° (-27° to 10°) for SS3A, 10° (-5° to 10°) for SS3B, 12° (0°-18°) for SS4, and 13° (4°-19°) for SS5. Overcorrection occurred in SS3A (4 cases) and SS3B (1 case).
conclusionSuccessful outcomes at 2 years depend on the interaction of key factors, such as intraoperative correction, residual growth potential as defined by preoperative SS, patient weight, spinal flexibility, and mechanobiological growth modulation. The advanced and validated planning tool used for the simulations incorporates these elements, integrating both biomechanical and biological growth dynamics to support a more precise and personalized surgical approach.
Indexed as
Identifiers
40880062What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.