Evidence map›Paper›PMID 40879993›Full record

SynthesisIrish journal of medical science2025

Different types of oesophageal reconstructions in the contemporary era: a systematic review and network meta-analysis.

Muireann Keating, Matthew G Davey, William Murray, Eamon Franics, Noel E Donlon

Abstract readSystematic ReviewNetwork Meta-Analysis
In one paragraph

Synthesis in Irish journal of medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muireann KeatingDepartment of Plastics and Reconstructive Surgery, St. James's Hospital, Dublin, Republic of Ireland. muireannkeating@gmail.com.ORCID http://orcid.org/0009-0007-2117-4084
Matthew G DaveyDepartment of Surgery, Royal College of Surgeons in Ireland, Dublin 2, Dublin, Republic of Ireland.
William MurrayDepartment of Surgery, Royal College of Surgeons in Ireland, Dublin 2, Dublin, Republic of Ireland.
Eamon FranicsDepartment of Plastics and Reconstructive Surgery, St. James's Hospital, Dublin, Republic of Ireland.
Noel E DonlonDepartment of Plastics and Reconstructive Surgery, St. James's Hospital, Dublin, Republic of Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOesophageal reconstruction is a complex operation that continues to present a surgical challenge associated with significant morbidity and its associated sequelae. The conventional gastric conduit remains the gold standard reconstructive technique when available. Alternative conduits for oesophageal replacement become necessary when the stomach is unavailable with common options for conduit creation being the jejunum and the colon. The aim of this systematic review and network meta-analysis was to interrogate outcomes in oesophageal reconstruction with gastric pull-up, colonic interposition and jejunal flap.

methodsA systematic review of three electronic databases (PubMed, EMBASE and SCOPUS) was undertaken. An NMA as per the PRISMA-NMA guidelines. Statistical analysis was carried out using R and Shiny.

resultsIn a total of 19 studies, 3927 patients were included; 79.5% (3123/3927) of patients underwent gastric pull-up; 13.5% (531/3927) of patients underwent colonic interposition; 7% (273/3927) of patients underwent jejunal flap as their reconstructive method. At NMA, there was no significant difference in anastomotic leak rates, mortality rates, stricture formation, necrosis and length of stay between the three reconstructive techniques. Trend results showed jejunal flap performed better than colonic interposition in length of stay and mortality rates.

conclusionAt present, the gastric conduit is the conventional and first choice for oesophageal reconstruction ab initio after oesophagostomy. Colonic interposition and jejunal free flap represent viable options and are associated with non-inferior short-term surgical outcomes when gastric pull-up is not available or feasible.

Indexed as

EsophagoplastyEsophagusPlastic Surgery ProceduresAnastomosis, SurgicalColonHumansJejunumStomachSurgical FlapsAnastomotic leakComplicationsOesophageal cancerOesophageal reconstructionOesophagectomy

Identifiers

PMID40879993
PMCPMC12769724

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.