Evidence map›Paper›PMID 40879991›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

Knockout Mice as an Experimental Model to Study the Biology of Inositol Pyrophosphates.

A Anindita, Jayraj Sen, Rashna Bhandari

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. The inositol pyrophosphate 5-InsPThe Journal of biological chemistry · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

A AninditaLaboratory of Cell Signalling, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India.
Jayraj SenLaboratory of Cell Signalling, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India.
Rashna BhandariLaboratory of Cell Signalling, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India. rashna@cdfd.org.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Knockout mice have served as excellent model systems to investigate the functions of specific mammalian proteins at the organismal level. Several studies on tissue-specific or whole-body depletion of individual IP6 kinase (IP6K) paralogs have shed light on myriad roles for their product, the inositol pyrophosphate 5-InsP

Indexed as

Inositol PhosphatesPhosphotransferases (Phosphate Group Acceptor)AnimalsFemaleMaleMiceMice, KnockoutTestisinositol hexakisphosphate kinaseInositol PhosphatesPhosphotransferases (Phosphate Group Acceptor)GenotypingHistologyImmunofluorescenceInositol hexakisphosphate kinase 1Mouse breeding

Identifiers

PMID40879991

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.