ReviewAdvances in experimental medicine and biology2025
Training-Induced Metabolic Adaptations in Skeletal Muscle.
Review in Advances in experimental medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Immune System as a Biosensor of Health and Athletic Performance.Scandinavian journal of medicine & science in sports · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolism involves not only the conversion of nutrient fuel into usable energy but also includes the synthesis, modification, and exchange of cellular building blocks, acting as a regulator and sensor of cellular activities. Various components within metabolic pathways can affect cellular responses. A significant portion of daily energy intake is necessary for sustaining life, and physical activity demands are added to an intricately integrated machinery. Studying elite human performance offers valuable information about the molecular, cellular, tissue, and overall body adjustments to intense metabolic demands. Moreover, understanding the mechanisms and pathways activated during exercise could potentially uncover new therapeutic targets for prescription in patient populations.In this book chapter, we will review the structural and functional peculiarities of our skeletal muscle cells, the myofibers. After this brief introduction, we will also give an overview of skeletal muscle metabolism depending on the intensity of the exercise. The metabolic demands and regulation of very intense, intermittent, or "stop-and-go" sports and long-lasting exercise efforts will be reviewed. The main reasons to explain the importance of carbohydrates in supporting ATP production in high-intensity exercise and the downregulation of fat metabolism at high aerobic exercise intensities in athletes are also discussed. The last section of this book chapter is devoted to the main metabolic adaptations to cardiorespiratory and resistance exercise training. These include exercise-induced skeletal muscle fiber-type transitions, changes in capillaries and myoglobin, improvements in mitochondrial content and function, changes in glycogen and intramuscular triglyceride skeletal muscle stores, and improvements in tolerance for acid-base imbalances.
Indexed as
Identifiers
40879953What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.