Evidence map›Paper›PMID 40879827›Full record

ReviewMarine biotechnology (New York, N.Y.)2025

Natural Products from Soft Corals in Taiwan: Insights into Chemical Taxonomy and Potential Interaction in Marine Environments.

Kuan-Ying Lai, Ping-Jyun Sung, Jyh-Horng Sheu, Tzu-Hsuan Tu, Shao-Liang Hsu, Crystal J McRae, Chih-Chuang Liaw

Abstract readReview
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In one paragraph

Review in Marine biotechnology (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kuan-Ying LaiDepartment of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung, 80424, Taiwan.
Ping-Jyun SungDepartment of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung, 80424, Taiwan.ORCID http://orcid.org/0000-0002-6644-9236
Jyh-Horng SheuDepartment of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung, 80424, Taiwan.ORCID http://orcid.org/0000-0002-1216-5991
Tzu-Hsuan TuDepartment of Oceanography, National Sun Yat-Sen University, Kaohsiung, 80424, Taiwan.ORCID http://orcid.org/0000-0003-4421-3342
Shao-Liang HsuMarine National Park Headquarters, National Park Service, Ministry of the Interior, Kaohsiung, 811017, Taiwan.
Crystal J McRaeDepartment of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung, 80424, Taiwan.ORCID http://orcid.org/0000-0002-3776-5862
Chih-Chuang LiawDepartment of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung, 80424, Taiwan. ccliaw@mail.nsysu.edu.tw.ORCID http://orcid.org/0000-0002-3552-3958

Funding

National Science and Technology Council MOST109-2611-M-110-019National Sun Yat-sen University Aim for the Top University Program 01C030205
6 · The paper itself

Abstract

Natural products, specifically secondary metabolites, produced by marine organisms, play crucial roles in their survival and performance. Research on natural products derived from marine organisms, particularly soft corals, has been ongoing for over 30 years in Taiwan, resulting in the isolation and identification of over 2000 unique compounds from 100 species of soft corals. These studies have not only uncovered bioactive compounds with potential useful applications but have also provided insights into the chemical evidence for the taxonomy of soft corals as well as the biological functions of these products within soft corals. Following the central dogma of molecular biology, this review notes that, according to the biosynthesis pathways, the types of natural products identified for seven clades of soft corals align with the updated phylogenetic system of soft corals based on DNA sequencing analysis. Thus, these natural products can serve as chemical evidence to support our understanding of soft coral taxonomy. Furthermore, to understand the influences of geographic factors on the production of natural products in soft corals, we compiled data on natural products from species repeatedly collected at different locations around Taiwan. Interestingly, the oxidation levels of briaranes in Briareum stechei and Junceella fragilis, and cembranes in Sclerophytum flexibile and Lobophytum crassum, tended to increase with rising seawater temperatures, while other soft corals also exhibited different metabolite profiles across spatial and temporal scales. Finally, we highlight the challenges and future perspectives in studying natural products from soft corals and propose that recent advancements in techniques, which offer comprehensive tools, such as mass spectral molecular networking, can significantly improve the elucidation of secondary metabolite structures. By addressing these challenges and leveraging new technologies, future research can provide novel insights into the roles that natural products play in marine chemistry. Collectively, this will contribute to a better understanding of marine biodiversity, the chemical dynamics of marine chemical ecology, and potential biotechnological applications.

Indexed as

AnthozoaBiological ProductsAnimalsPhylogenySeawaterTaiwanBiological ProductsMarineNatural productSoft corals

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.